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Carlo Salvarani
University of Modena and Reggio Emilia
Physical therapyGiant cell arteritisPolymyalgia rheumaticaDiabetes mellitusMedicine
732Publications
70H-index
19.5kCitations
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Publications 766
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Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is a group of systemic vasculitides that predominantly affect small vessels, including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). Pulmonary involvement is frequently observed in AAV patients, with various possible phenotypes in the different diseases. In the last years, among the possible types of lung involvement, a growing interest has ...
#1Michele Antonelli (University of Parma)H-Index: 2
#2Fabio FirenzuoliH-Index: 1
Last. Davide DonelliH-Index: 2
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Literature reviews can be directly used by clinicians and other health professionals to support many decision-making processes. This review aims to offer health professionals an essential practical guide to critically evaluate and properly understand results of review articles published in the scientific literature. An evidence-based methodological review with step-by-step theoretical concepts and practical suggestions was developed. Key steps of this guide are: to consider the topic and the res...
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#1Giulia Cassone (University of Modena and Reggio Emilia)H-Index: 6
#2Andreina Teresa Manfredi (University of Modena and Reggio Emilia)H-Index: 15
Last. Marco Sebastiani (University of Modena and Reggio Emilia)H-Index: 26
view all 7 authors...
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease affecting 0.5–1% of the population worldwide. Interstitial lung disease (ILD) is a serious pulmonary complication of RA and it is responsible for 10–20% of mortality, with a mean survival of 5–8 years. However, nowadays there are no therapeutic recommendations for the treatment of RA-ILD. Therapeutic options for RA-ILD are complicated by the possible pulmonary toxicity of many disease modifying anti-rheumatic drugs (DMARDs)...
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#1Nicola UghiH-Index: 7
Last. Carlo Alberto Scirè (University of Ferrara)H-Index: 20
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OBJECTIVE: to provide evidence-based up-to-date recommendations for the management of patients with a definite diagnosis of polymyalgia rheumatica (PMR). METHODS: A systematic literature review was performed to find the existing clinical practice guidelines (CPGs) on PMR and the framework of the Guidelines International Network Adaptation Working Group was used to appraise (AGREE II), synthesize, and customize the recommendations according to the needs of the Italian healthcare context. Rheumato...
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#1Edoardo Conticini (UNISI: University of Siena)
#2A Negro (AUSL: Academy for Urban School Leadership)
Last. Carlo Salvarani (AUSL: Academy for Urban School Leadership)H-Index: 70
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Gitelman syndrome (GS) is an inherited salt-wasting tubulopathy characterized by hypocalciuria, hypokalemia, hypomagnesemia and metabolic alkalosis, due to inactivating mutations in the SLC12A3 gene. Symptoms may be systemic, neurological, cardiovascular, ophthalmological or musculoskeletal. We describe a 70 year-old patient affected by recurrent arthralgias, hypoesthesia and hyposthenia in all 4 limbs and severe hypokalemia, complicated by atrial flutter. Moreover, our patient reported eating l...
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#1Mariele Gatto (UNIPD: University of Padua)H-Index: 25
#2Francesca Saccon (UNIPD: University of Padua)H-Index: 5
Last. Fulvia Ceccarelli (Sapienza University of Rome)H-Index: 27
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OBJECTIVE: To investigate predictors of response, remission, low disease activity (LDA), damage and drug discontinuation in patients with systemic lupus erythematosus (SLE) treated with belimumab. METHODS: We retrospectively analysed data of a multicentre cohort of SLE patients receiving intravenous belimumab. Proportion of patients achieving remission, LDA and SLE Responder Index-4 (SRI-4) were evaluated. SLICC damage index (SDI) was calculated yearly. Predictors of outcomes were investigated b...
1 CitationsSource
Introduction: Interstitial lung disease (ILD) is a frequent extra-articular manifestation of Rheumatoid arthritis (RA), but nowadays there are no randomized controlled clinical trials to support therapeutic guidelines. RA-ILD, especially with UIP pattern, shares some similarities with idiopathic pulmonary fibrosis, suggesting a possible role of antifibrotic therapy in these patients. To date, there are no published data supporting the use of pifenidone in RA-ILD.We describe for the first time tw...
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#1Nicolò Girolimetto (University of Naples Federico II)H-Index: 3
#2Pierluigi MacchioniH-Index: 36
Last. Carlo Salvarani (University of Modena and Reggio Emilia)H-Index: 70
view all 13 authors...
OBJECTIVES: The aim of this study was to explore the link between specific sonographic findings and Leeds Dactylitis Index basic (LDI-b) score in psoriatic arthritis (PsA) patients with hand dactylitis. METHODS: Ninety-one hand dactylitis were evaluated in a multicentre study for the presence of pain, functional limitation and tenderness (2-point scale) and LDI-b score. Dactylitic fingers were investigated using high-frequency US in grey scale (GS) and power Doppler (PD). According to median LDI...
#1Martina BonaciniH-Index: 3
#2Alessandra SorianoH-Index: 13
Last. Alessandro ZerbiniH-Index: 4
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Non-infectious uveitis are intraocular inflammatory conditions caused by dysregulated activation of the immune response without any detectable infectious agents. The aim of this study was to explore potential markers and therapeutic targets for two distinct types of non-infectious uveitis associated with Behcet's disease (BD) and Vogt Koyanagi Harada (VKH) disease. Concentrations of 27 cytokines were investigated in aqueous humor (AH) samples from patients with active uveitis vs. healthy control...
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#1Caterina VacchiH-Index: 4
Last. Marco SebastianiH-Index: 26
view all 6 authors...
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disease characterized by joint and extra-articular involvement. Among them, interstitial lung disease (ILD) is one of the most common and severe extra-articular manifestations, with a negative impact on both therapeutic approach and overall prognosis. ILD can occur at any point of the natural history of RA, sometimes before the appearance of joint involvement. Since no controlled studies are available, the therapeutic approach to RA-...
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