Clemens von Schacky
Ludwig Maximilian University of Munich
65Publications
25H-index
3,161Citations
Publications 65
Newest
Dominik Berliner10
Estimated H-index: 10
(Hannover Medical School),
Sarah Mattern + 11 AuthorsRosemarie Kiefl11
Estimated H-index: 11
Abstract Background Epidemiologic studies on the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in heart failure are scarce, while one large intervention trial demonstrated a modest benefit. Methods This is a secondary analysis from the Interdisciplinary Network Heart Failure (INH) program. Patients hospitalized for systolic heart failure were enrolled and followed for 36 months. At baseline, whole blood samples from 899 patients were analyzed for fatty acid compo...
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Published on Jul 1, 2018in Journal of Hypertension 3.15
Mark G. Filipovic1
Estimated H-index: 1
,
Stefanie Aeschbacher11
Estimated H-index: 11
+ 10 AuthorsThomas F. Lüscher118
Estimated H-index: 118
Background:Omega-3 fatty acids (n − 3 FA) may have blood pressure (BP)-lowering effects in untreated hypertensive and elderly patients. The effect of n − 3 FA on BP in young, healthy adults remains unknown. The Omega-3 Index reliably reflects an individuals’ omega-3 status. We hypothesized that the
1 Citations Source Cite
Clemens von Schacky25
Estimated H-index: 25
(Ludwig Maximilian University of Munich),
William S. Harris73
Estimated H-index: 73
(University of South Dakota)
Abstract As currently defined, the Omega-3 Index comprises eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), but not docosapentaenoic acid (DPA) in erythrocytes. In fish and many fish oils DPA is detectable (along with EPA and DHA), but sources rich in DPA are scarce. Purified DPA is available, and DPA is a precursor of biologically active molecules, but much remains to be learned about the effects of DPA in humans. In epidemiologic studies, erythrocyte DPA did not predict risk for tot...
1 Citations Source Cite
Jesús Castro-Marrero10
Estimated H-index: 10
(Autonomous University of Barcelona),
Maria Cleofé Zaragozá2
Estimated H-index: 2
(Autonomous University of Barcelona)
+ 3 AuthorsClemens von Schacky25
Estimated H-index: 25
(Ludwig Maximilian University of Munich)
Abstract Background Several studies have suggested that low levels of omega-3 fatty acids (n-3 PUFAs) including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with cardiovascular risk, major depression, sleep problems, inflammation and other health-related issues. So far, however, erythrocyte PUFA status in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) has not been established. This study aimed to determine whether n-3 PUFA content and omega-3 index are a...
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Published on Sep 1, 2017in Maturitas 3.31
Rafael Sánchez-Borrego10
Estimated H-index: 10
,
Clemens von Schacky25
Estimated H-index: 25
(Ludwig Maximilian University of Munich)
+ 6 AuthorsNicolás Mendoza13
Estimated H-index: 13
(University of Granada)
Abstract The consumption of long-chain omega-3 polyunsaturated fatty acids (LCO3-PUFAs) has shown a great variety of beneficial effects, including cardiovascular, metabolic and inflammatory effects, which make them interesting for the postmenopausal woman. Because LCO3-PUFAs could be effective and safe during this period, a panel of experts from the Spanish Menopause Society met to establish a set of recommendations for their use in postmenopausal women based on the best available evidence. The ...
3 Citations Source Cite
Published on Oct 15, 2017in Journal of Clinical Sleep Medicine 3.40
Janine Tittus , Marie Theres Huber + 4 AuthorsClemens von Schacky25
Estimated H-index: 25
Study Objectives: Erythrocyte levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (Omega-3 Index) were previously found to be associated with obstructive sleep apnea (OSA) at very low levels ( 5.7% in an intervention trial with EPA and DHA in OSA, comorbidities of OSA suggest a target range of 8% to 11%.
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Published on Jun 1, 2017in European Journal of Nutrition 4.42
Clemens von Schacky25
Estimated H-index: 25
(Ludwig Maximilian University of Munich),
Adrian Passow1
Estimated H-index: 1
,
Rosemarie Kiefl11
Estimated H-index: 11
(Ludwig Maximilian University of Munich)
Purpose High, but not low levels of trans-fatty acids (TFA) in erythrocytes are associated with increased mortality. Current erythrocyte TFA levels in Europe are not known.
7 Citations Source Cite
Published on Aug 24, 2017in Nutrients 4.20
Sowmyanarayanan V. Thuppal4
Estimated H-index: 4
(Purdue University),
Clemens von Schacky25
Estimated H-index: 25
(Ludwig Maximilian University of Munich)
+ 5 AuthorsRegan L. Bailey13
Estimated H-index: 13
(Purdue University)
Little is known about the relationship between perceptions of nutrient adequacy and biomarkers of nutrition status. This cross-sectional study of U.S. and German adults (n = 200; 18–80 years) compared dietary practices, knowledge, and beliefs of omega-3 fatty acids (O3-FA) with the omega-3 index (O3-I), an erythrocyte-based biomarker associated with cardiovascular disease (CVD) risk. More than half of adults believed that O3-FAs are beneficial for heart and brain health and could correctly ident...
1 Citations Source Cite
Published on Jun 19, 2017in Nutrients 4.20
Anton Köhler3
Estimated H-index: 3
,
Johanna Heinrich1
Estimated H-index: 1
,
Clemens von Schacky25
Estimated H-index: 25
A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerability of EPA and DHA in a novel source: a variety of sausages. We screened 96 healthy volunteers, and recruited 44 with an Omega-3 Index <5%. Participants were randomly assigned to rec...
1 Citations Source Cite
Published on Jan 1, 2017in Journal of Clinical Lipidology 3.58
Graciela Delgado19
Estimated H-index: 19
(Heidelberg University),
Bernhard K. Krämer46
Estimated H-index: 46
(Heidelberg University)
+ 3 AuthorsMarcus E. Kleber45
Estimated H-index: 45
(University of Jena)
Background The association of polyunsaturated omega-3 and omega-6 fatty acids with mortality has been extensively studied. Far less is known about the association of omega-9 monounsaturated fatty acids (omega-9 MUFA) with mortality. Objective We aimed to study the association of individual omega-MUFA with all-cause and cardiovascular mortality. Methods Omega-9 MUFA concentrations were measured in erythrocytes in 3259 patients participating in the Ludwigshafen Risk and Cardiovascular Health Study...
5 Citations Source Cite
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