Ewa Sewerynek
University of Texas Health Science Center at San Antonio
EndocrinologyMelatoninLipid peroxidationDiabetes mellitusMedicine
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Publications 86
#1Ewa SewerynekH-Index: 21
#2Karol CieślakH-Index: 2
Last. Michał StussH-Index: 6
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Introduction: The goal of the study was an evaluation of serum vitamin D concentrations in healthy young women. Material and methods: A total of 106 healthy women, aged 20–30 years, were included in the study. Monthly evaluation — for three months — of the effects of calcium (500 mg) and vitamin D (1500 IU) administration in women with baseline values of vitamin D 20 ng/mL (Group 2). Additionally, calcium and PTH concentrations were assessed at the study onset and after a three-month supplementa...
2 CitationsSource
#1Susan M. DenekeH-Index: 8
#2Ewa SewerynekH-Index: 7
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#1Wojciech Pluskiewicz (Medical University of Silesia)H-Index: 19
#2Piotr Adamczyk (Medical University of Silesia)H-Index: 12
Last. Bogna Drozdzowska (Medical University of Silesia)H-Index: 14
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AbstractPurpose: The aim of the study was the presentation of osteoporotic fracture prediction in men.Methods: Eight-hundred and one men at the mean age of 70.8 ± 9.31 years were examined. The 10-year fracture prediction was established, using the FRAX™ calculator and Garvan nomogram.Results: The mean value for any fracture and hip fracture probabilities for FRAX were 7.26 ± 5.4% and 3.68 ± 4.25%, respectively. For Garvan fracture, risk values were 26.44 ± 23.83% and 12.02 ± 18.1%. The mean conf...
3 CitationsSource
Context: Recent research results have confirmed the high significance of the OPG/RANK/RANKL system in the development of bone diseases. Aim: The aim of the reported study was to assess gene expression levels of the OPG/RANK/RANKL system in peripheral blood mononuclear cells (PBMCs) after strontium ranelate (SR) and ibandronate administered to patients with postmenopausal osteoporosis. Patients and Methods: A total of 89 postmenopausal women, aged 51 to 85 years, patients of the Outpatient Clinic...
9 CitationsSource
#1Michalina Marcinkowska (Poznan University of Medical Sciences)H-Index: 7
#2Wanda Horst-Sikorska (Poznan University of Medical Sciences)H-Index: 10
Last. Ewa SewerynekH-Index: 21
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Wstep: Osteoporoza z racji zmian demograficznych oraz nieprawidlowego stylu zycia spoleczenstw rozwinietych stala sie powaznym problemem spolecznym. Zlamanie blizszego konca kości udowej stanowi jej najpowazniejsze powiklanie, związane z duzą śmiertelnością lub trwalymi nastepstwami. Celem pracy byla ocena wplywu wybranych czynnikow socjoekonomicznych i czasu interwencji chirurgicznej na rokowanie. Material i metody: W badaniu uczestniczylo 148 pacjentow (114 kobiet i 34 mezczyzn) w wieku od 48 ...
1 Citations
#1Ewa SewerynekH-Index: 21
Last. Michał StussH-Index: 6
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Introduction The aim of the study was to assess the role of patient counselling, nurse assistance and effects of biochemical examinations in adherence of women with postmenopausal osteoporosis to alendronate 70 administration over 12 months of therapy.
7 CitationsSource
Glucocorticoids are quite commonly used in the treatment of many diseases and are one of the most common causes of secondary osteoporosis. Osteoporosis associated with chronic steroid therapy, appears to be an important medical problem. In the USA, glucocorticoids are prescribed to 1 million patients a year. Data from the UK reveal as many as 1.6 million prescriptions for steroid agents within 10 years. Glucocorticoids are used by 0.9% of the total population and approximately 2.5% in the age gr...
2 CitationsSource
#1Nadia BrylH-Index: 2
Last. Ewa SewerynekH-Index: 21
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Objective: The aim of the study was to examine the impact of social competence of physicians on the effectiveness of patient compliance and persistence with therapy. Material and methods: The study included physicians and their patients, previously diagnosed with osteoporosis, and eligible to receive pharmacological treatment. The physicians were evaluated with the Social Competence Questionnaire involving three dimensions: social exposure, intimacy and assertiveness, as well as in the combined ...
2 Citations
Introduction Autoimmune thyroid disease (AITD) is associated with both genetic and environmental factors which lead to the overactivity of immune system. Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene polymorphisms belong to the main genetic factors determining the susceptibility to AITD (Hashimoto's thyroiditis, HT and Graves' disease, GD) development. The aim of the study was to evaluate the relationship between CTLA-4 polymorphisms (A49G, 1822 C/T and CT60 A/G) and HT and/or GD in Polish pati...
18 CitationsSource
Steroid-induced osteoporosis is a textbook example of the secondary type of this medical condition. Glucocorticosteroids suppress bone formation by their direct and indirect effect on osteoblasts, osteoclasts and osteocytes, increasing their resorption and, eventually, leading to negative bone balance. A clinical problem arises regarding the fact that approximately 50% of patients on chronic steroid therapy undergo asymptomatic bone fractures. The treatment mode includes minimising the dose of a...
5 Citations