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Brenden Tervo-Clemmens
University of Pittsburgh
11Publications
3H-index
97Citations
Publications 11
Newest
Abstract The 21-site Adolescent Brain Cognitive Development (ABCD) study provides an unparalleled opportunity to characterize functional brain development via resting-state functional connectivity (RSFC) and to quantify relationships between RSFC and behavior. This multi-site data set includes potentially confounding sources of variance, such as differences between data collection sites and/or scanner manufacturers, in addition to those inherent to RSFC (e.g., head motion). The ABCD project prov...
#1Alina Quach (University of Pittsburgh)H-Index: 1
#2Brenden Tervo-Clemmens (University of Pittsburgh)H-Index: 3
Last.Beatriz Luna (University of Pittsburgh)H-Index: 44
view all 0 authors...
Previous research indicates that risk for substance use is associated with poor inhibitory control. However, it remains unclear whether at risk youth use follow divergent patterns of inhibitory control development. As part of the longitudinal National Consortium on Adolescent Neurodevelopment and Alcohol (NCANDA) study, participants (N = 113, baseline age: 12-21) completed a rewarded antisaccade task during fMRI, with up to three time points. We examined whether substance use risk factors, inclu...
Objective:The authors created normative growth charts of amygdala functional connectivity in typically developing youths, assessed age-associated deviations of these trajectories in youths with psychosis spectrum disorders, and explored how these disruptions are related to clinical symptomatology.Methods:Resting-state functional neuroimaging data from four samples (three cross-sectional, one longitudinal) were collected for 1,062 participants 10–25 years of age (622 typically developing control ...
#1Brenden Tervo-Clemmens (University of Pittsburgh)H-Index: 3
#2Daniel Simmonds (University of Pittsburgh)H-Index: 5
Last.Beatriz Luna (University of Pittsburgh)H-Index: 44
view all 8 authors...
Abstract Background Retrospective neuroimaging studies have suggested an association between early cannabis onset and later neurocognitive impairment. However, these studies have been limited in their ability to distinguish substance use risk factors from cannabis-induced effects on neurocognition. We used a prospective cohort design to test whether neurocognitive differences preceded cannabis onset (substance use risk model) and if early cannabis use was associated with poorer neurocognitive de...
#1Brenden Tervo-Clemmens (University of Pittsburgh)H-Index: 3
#2Daniel Simmonds (University of Pittsburgh)H-Index: 5
Last.Beatriz Luna (University of Pittsburgh)H-Index: 44
view all 6 authors...
Abstract Given prior reports of adverse effects of cannabis use on working memory, an executive function with a protracted developmental course during adolescence, we examined associations between developmental patterns of cannabis use and adult working memory (WM) processes. Seventy-five adults with longitudinal assessments of cannabis use (60 with reported use, 15 with no reported use) and prenatal drug exposure assessment completed a spatial WM task during fMRI at age 28. All subjects passed ...
#1Brenden Tervo-Clemmens (University of Pittsburgh)H-Index: 3
#2Alina Quach (University of Pittsburgh)H-Index: 1
Last.Duncan B. Clark (University of Pittsburgh)H-Index: 53
view all 7 authors...
Risk for substance use disorder (SUD) is associated with poor response inhibition and heightened reward sensitivity. During adolescence, incentives improve performance on response inhibition tasks and increase recruitment of cortical control areas (Geier et al., 2010) associated with SUD (Chung et al., 2011). However, it is unknown whether incentives moderate the relationship between response inhibition and trait-level psychopathology and personality features of substance use risk. We examined t...
#1Beatriz Luna (University of Pittsburgh)H-Index: 44
#2Scott MarekH-Index: 2
Last.Rajpreet ChahalH-Index: 2
view all 5 authors...
Brains systems undergo unique and specific dynamic changes at the cellular, circuit, and systems level that underlie the transition to adult-level cognitive control. We integrate literature from these different levels of analyses to propose a novel model of the brain basis of the development of cognitive control. The ability to consistently exert cognitive control improves into adulthood as the flexible integration of component processes, including inhibitory control, performance monitoring, and...
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