David Wesley Dowdy
Johns Hopkins University
Intensive care medicineImmunologyTuberculosisPopulationMedicine
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Publications 276
#1Stefan Baral (Johns Hopkins University)H-Index: 42
#2Sharmistha Mishra (St. Michael's Hospital)H-Index: 16
Last. David Wesley Dowdy (Johns Hopkins University)H-Index: 38
view all 5 authors...
#1David Wesley Dowdy (Johns Hopkins University)H-Index: 38
#2Alice Zwerling (U of O: University of Ottawa)
Last. Maria W. Merritt (Johns Hopkins University)H-Index: 12
view all 7 authors...
In making policy decisions with constrained resources, an important consideration is the impact of alternative policy options on social justice. Social justice considers interactions between indivi...
#1Hyejeong Hong (Johns Hopkins University)H-Index: 2
#2David Wesley Dowdy (Johns Hopkins University)H-Index: 38
Last. Jason E. Farley (Johns Hopkins University)H-Index: 15
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Purpose Hearing loss, resulting from aminoglycoside ototoxicity, is common among patients with drug-resistant tuberculosis (DR-TB). Those with pre-existing hearing loss are at particular risk of clinically important hearing loss with aminoglycoside-containing treatment than those with normal hearing at baseline. This study aimed to identify factors associated with pre-existing hearing loss among patients being treated for DR-TB in South Africa. Method Cross-sectional analysis nested within a clu...
#1Tania Reza (UCSF: University of California, San Francisco)H-Index: 1
#2Talemwa NalugwaH-Index: 1
Last. Austin Tucker (Johns Hopkins University)H-Index: 1
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BACKGROUND: Delays in diagnosis and treatment of tuberculosis (TB) remain common in high-burden countries. To improve case detection, substantial investments have been made to scale-up Xpert MTB/RIF (Xpert), a cartridge-based nucleic acid amplification test that can detect TB within 2 hours, as a replacement for sputum smear microscopy. However, the optimal strategy for implementation of Xpert testing remains unclear. METHODS: The Xpert Performance Evaluation for Linkage to Tuberculosis Care (XP...
#1Kunihiro Matsushita (Johns Hopkins University)H-Index: 50
#2Ning Ding (Johns Hopkins University)H-Index: 2
Last. Junichi Ishigami (Johns Hopkins University)H-Index: 5
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Background: Whether cardiovascular disease (CVD) and its traditional risk factors predict severe coronavirus disease 2019 (COVID-19) is uncertain, in part, because of potential confounding by age and sex. Methods: We performed a systematic review of studies that explored pre-existing CVD and its traditional risk factors as risk factors of severe COVID-19 (defined as death, acute respiratory distress syndrome, mechanical ventilation, or intensive care unit admission). We searched PubMed and Embas...
1 CitationsSource
#1H-Y. Kim (Johns Hopkins University)
#2Colleen Hanrahan (Johns Hopkins University)H-Index: 16
Last. J. F. P. Bridges (OSU: Ohio State University)
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BACKGROUND: There has been slow uptake of isoniazid preventive therapy (IPT) among people living with HIV (PLWH).METHODS: We surveyed adults recently diagnosed with HIV in 14 South African primary health clinics. Based on the literature and qualitative interviews, sixteen potential barriers and facilitators related to preventive therapy among PLWH were selected. Best-worst scaling (BWS) was used to quantify the relative importance of the attributes. BWS scores were calculated based on the freque...
#1Talemwa NalugwaH-Index: 1
#2Priya B. SheteH-Index: 8
Last. David Moore (Lond: University of London)H-Index: 95
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BACKGROUND: Many high burden countries are scaling-up GeneXpert(R) MTB/RIF (Xpert) testing for tuberculosis (TB) using a hub-and-spoke model. However, the effect of scale up on reducing TB has been limited. We sought to characterize variation in implementation of referral-based Xpert TB testing across Uganda, and to identify health system factors that may enhance or prevent high-quality implementation of Xpert testing services. METHODS: We conducted a cross-sectional study triangulating quantita...
#1H-Y Kim (Johns Hopkins University)
#1Hae Young Kim (Johns Hopkins University)H-Index: 3
Last. Christopher J. Hoffmann (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 23
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BACKGROUND: Correctional inmates are at a high risk of tuberculosis (TB). The optimal approach to screening this population is unclear.METHODS: We retrospectively reviewed records from TB screening in 64 correctional facilities in South Africa between January 2015 and July 2016. Inmates received symptom screening (any of cough, fever, weight loss, or night sweats) combined with digital chest X-ray (CXR), when available. CXRs were assessed as 'abnormal' or with no abnormalities. Inmates with eith...
#1Hyejeong Shin (Johns Hopkins University)
#2Lucky G. Ngwira (LSTM: Liverpool School of Tropical Medicine)H-Index: 3
Last. David Wesley Dowdy (Johns Hopkins University)H-Index: 38
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OBJECTIVES: To mitigate the economic burden of tuberculosis (TB), it is important to fully understand the costs of TB treatment from the patient perspective. We therefore sought to quantify the patient-incurred cost of TB treatment in rural Malawi, with specific focus on costs borne by patients requiring inpatient hospitalisation. METHODS: We conducted a cross-sectional survey of 197 inpatients and 156 outpatients being treated for TB in rural Malawi. We collected data on out-of-pocket costs and...