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James J. DiNicolantonio
Mount Sinai St. Luke's and Mount Sinai Roosevelt
155Publications
24H-index
2,157Citations
Publications 155
Newest
Published on Dec 1, 2018in Trends in Cardiovascular Medicine 4.60
Carl J. Lavie82
Estimated H-index: 82
,
James J. DiNicolantonio24
Estimated H-index: 24
,
James H. O'Keefe52
Estimated H-index: 52
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Published on Jun 1, 2019
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Published on Mar 4, 2019in Journal of Dietary Supplements
Mark F. McCarty25
Estimated H-index: 25
,
James H. O'Keefe52
Estimated H-index: 52
(UMKC: University of Missouri–Kansas City),
James J. DiNicolantonio24
Estimated H-index: 24
ABSTRACTAlthough clinical trials with glucosamine in osteoarthritis have yielded mixed results, leading to doubts about its efficacy, the utility of glucosamine for preventing joint destruction and inflammation is well documented in rodent models of arthritis, including models of spontaneous osteoarthritis. The benefit of oral glucosamine in adjuvant arthritis is markedly dose dependent, likely reflecting a modulation of tissue levels of UDP-N-acetylglucosamine that in turn influences mucopolysa...
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Published on Sep 1, 2018in Progress in Cardiovascular Diseases 6.75
James J. DiNicolantonio24
Estimated H-index: 24
,
James H. O'Keefe52
Estimated H-index: 52
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Published on Aug 18, 2018in Nutrition and Cancer 2.26
Mark F. McCarty25
Estimated H-index: 25
,
James J. DiNicolantonio24
Estimated H-index: 24
AbstractMany cancers and pre-cancerous lesions convert membrane-bound arachidonic acid (AA) to eicosanoids that promote the survival, growth, and spread of cancer. In contrast, the long-chain omega-3s eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can competitively inhibit AA’s interaction with the enzymes that give rise to eicosanoids, while acting as precursors for alternative eicosanoids which oppose cancer development and growth. Hence, minimizing the AA content of cancer membran...
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Published on Jul 1, 2018in Current Opinion in Cardiology 2.01
James J. DiNicolantonio24
Estimated H-index: 24
,
James H. O'Keefe52
Estimated H-index: 52
1 Citations Source Cite
Published on Jul 1, 2018in British Journal of Sports Medicine 7.87
James J. DiNicolantonio24
Estimated H-index: 24
,
James H. O'Keefe52
Estimated H-index: 52
,
William Wilson2
Estimated H-index: 2
In animal studies, sugar has been found to produce more symptoms than is required to be considered an addictive substance. Animal data has shown significant overlap between the consumption of added sugars and drug-like effects, including bingeing, craving, tolerance, withdrawal, cross-sensitisation, cross-tolerance, cross-dependence, reward and opioid effects. Sugar addiction seems to be dependence to the natural endogenous opioids that get released upon sugar intake. In both animals and humans,...
7 Citations Source Cite
Published on May 1, 2018in Progress in Cardiovascular Diseases 6.75
Andrew Elagizi3
Estimated H-index: 3
,
Carl J. Lavie82
Estimated H-index: 82
(UQ: University of Queensland)
+ 3 AuthorsRichard V. Milani64
Estimated H-index: 64
(UQ: University of Queensland)
Abstract The potential cardiovascular (CV) disease (CVD) benefits of Omega-3 Polyunsaturated Fatty Acids (OM3) have been intensely studied and debated for decades. Initial trials were performed in patients with low use of maximal medical therapy for CVD, and reported significant mortality benefits with the use of 1 g/day OM3 intervention following myocardial infarction (MI). More recent studies, including cohorts of patients receiving modern guideline directed medical therapy for CVD, have often...
8 Citations Source Cite
Published on Mar 15, 2018in The Ochsner journal
Mark F. McCarty25
Estimated H-index: 25
,
James H. O'Keefe52
Estimated H-index: 52
,
James J. DiNicolantonio24
Estimated H-index: 24
Background: Glutathione is a key scavenging antioxidant that opposes the proinflammatory signaling of hydrogen peroxide. Boosting cellular glutathione levels may have broad utility in the prevention and treatment of disorders driven by oxidative stress. Supplemental N-acetylcysteine has been employed for this purpose. Could supplemental glycine likewise promote glutathione synthesis? Methods: We conducted a review of the pertinent literature using PubMed. Results: Tissue glycine levels are lower...
1 Citations
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