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Alain Luxembourg
Merck & Co.
60Publications
20H-index
1,597Citations
Publications 60
Newest
Published on Apr 1, 2019in Gynecologic Oncology 4.54
Anna R. Giuliano65
Estimated H-index: 65
,
Elmar A. Joura32
Estimated H-index: 32
(Medical University of Vienna)
+ 12 AuthorsMark H. Stoler62
Estimated H-index: 62
(University of Virginia Health System)
Abstract Objective Nine-valent human papillomavirus (9vHPV) vaccine efficacy against disease and cervical surgeries related to all nine vaccine components was assessed compared with a historic placebo population. This was not assessed in the 9vHPV vaccine efficacy trial since the trial was quadrivalent HPV (qHPV) vaccine-controlled, efficacy was measured for the five HPV types covered only by 9vHPV vaccine (HPV31/33/45/52/58), but not the four types covered by both vaccines (HPV6/11/16/18). Meth...
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Published on Jan 2, 2019in Human Vaccines & Immunotherapeutics 2.23
Ana María Guevara2
Estimated H-index: 2
,
Eugenio Suarez4
Estimated H-index: 4
(University of Chile)
+ 7 AuthorsAlain Luxembourg20
Estimated H-index: 20
(Merck & Co.)
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Published on Aug 1, 2018in Obstetrics & Gynecology 4.98
Suzanne M. Garland61
Estimated H-index: 61
(University of Virginia),
Elmar A. Joura32
Estimated H-index: 32
(University of Virginia)
+ 28 AuthorsMauricio Hernandez-Avila3
Estimated H-index: 3
(University of Virginia)
OBJECTIVE:To estimate the proportion of vulvar and vaginal low-grade and high-grade squamous intraepithelial lesions (LSILs and HSILs) in females 15–26 years of age attributable to 14 human papillomavirus (HPV) genotypes (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59).METHODS:A post hoc anal
2 Citations Source Cite
Published on Jun 5, 2018in The Journal of Infectious Diseases 5.19
Suzanne M. Garland61
Estimated H-index: 61
(Royal Children's Hospital),
Punnee Pitisuttithum40
Estimated H-index: 40
(Mahidol University)
+ 31 AuthorsR. Samakoses1
Estimated H-index: 1
1 Citations Source Cite
Published on May 20, 2018in Journal of Clinical Oncology 26.36
Evan R. Meyers1
Estimated H-index: 1
(Duke University),
Alain Luxembourg20
Estimated H-index: 20
(Merck & Co.)
+ 1 AuthorsChristine Velicer19
Estimated H-index: 19
(Merck & Co.)
5530Background: Few studies have reported the burden of Pap abnormalities associated with the specific HPV types targeted by HPV vaccines. The purpose of this analysis is to estimate prevalence of ...
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Published on May 20, 2018in Journal of Clinical Oncology 26.36
Stephen E. Goldstone26
Estimated H-index: 26
,
Anna R. Giuliano65
Estimated H-index: 65
+ 1 AuthorsAlain Luxembourg20
Estimated H-index: 20
(Merck & Co.)
1553Background: The quadrivalent human papillomavirus (qHPV) vaccine prevented HPV6/11/16/18-related persistent infection and external genital lesions in young men in an international, randomized, placebo-controlled pivotal efficacy study. We report the end-of-study analysis of a long-term follow up (LTFU) extension study that assessed the effectiveness and immunogenicity of the qHPV vaccine through 10 years after the first dose. Methods: In the 3-year base study, young men (16-26 years old) wer...
1 Citations Source Cite
Published on Feb 1, 2018in Human Vaccines & Immunotherapeutics 2.23
Edson Duarte Moreira Junior (Obras Sociais Irmã Dulce), Anna R. Giuliano65
Estimated H-index: 65
+ 11 AuthorsA Krick (Merck & Co.)
aCentro de Pesquisa Clinica, Associacao Obras Sociais Irma Dulce and Oswaldo Cruz Foundation, Brazilian Ministry of Health, Salvador, Bahia, Brazil; bDepartment of Cancer Epidemiology, Center for Infection Research (CIRC), Moffitt Cancer Center, Tampa, Florida, USA; cCenter for Clinical Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; dDepartment of Clinical Science, University of Bergen/Womens Clinic, Haukeland University Hospital, Bergen, Nor...
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Published on Dec 1, 2017in Papillomavirus Research
Ángela María Ruiz Sternberg5
Estimated H-index: 5
(Del Rosario University),
Edson D. Moreira9
Estimated H-index: 9
(Obras Sociais Irmã Dulce)
+ 21 AuthorsAlejandro Victoria1
Estimated H-index: 1
Moreira Junior, Edson Duarte. Associacao Obras Sociais Irma Dulce / Fundacao Oswaldo Cruz. Centro de Pesquisas Goncalo Moniz. Salvador, BA, Brasil. a Clinical Research Group, Universidad del Rosario, Bogota, Colombia b Associacao Obras Sociais Irma Dulce and Oswaldo Cruz Foundation, Brazilian Ministry of Health, Bahia, Brazil c Foundation Clinical Research Center CIC, Medellin, Colombia d Research Center on Public Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico e Via Lib...
1 Citations Source Cite
Published on Nov 2, 2017in Expert Review of Vaccines 4.27
Alain Luxembourg20
Estimated H-index: 20
(Merck & Co.),
Erin Moeller7
Estimated H-index: 7
(Merck & Co.)
ABSTRACTIntroduction: The 9-valent human papillomavirus (9vHPV) vaccine covers the same HPV types (6/11/16/18) as the quadrivalent HPV (qHPV) vaccine and 5 additional cancer-causing types (31/33/45/52/58). Epidemiological studies indicate that the 9vHPV vaccine could prevent approximately 90% of cervical cancers, 70–85% of high-grade cervical dysplasia (precancers), 85–95% of HPV-related vulvar, vaginal, and anal cancers, and 90% of genital warts.Areas covered: Study design features and key find...
6 Citations Source Cite
Published on Nov 1, 2017in The Lancet 53.25
Warner K. Huh43
Estimated H-index: 43
(University of Alabama at Birmingham),
Elmar A. Joura32
Estimated H-index: 32
(Medical University of Vienna)
+ 25 AuthorsAngelica Lindén Hirschberg34
Estimated H-index: 34
(Karolinska University Hospital)
Summary Background Primary analyses of a study in young women aged 16–26 years showed efficacy of the nine-valent human papillomavirus (9vHPV; HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58) vaccine against infections and disease related to HPV 31, 33, 45, 52, and 58, and non-inferior HPV 6, 11, 16, and 18 antibody responses when compared with quadrivalent HPV (qHPV; HPV 6, 11, 16, and 18) vaccine. We aimed to report efficacy of the 9vHPV vaccine for up to 6 years following first administration and a...
38 Citations Source Cite
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