Match!
LeonardGabriel
EndocrinologyDevelopmental psychologyPsychologyDiabetes mellitusMedicine
98Publications
35H-index
4,032Citations
What is this?
Publications 99
Newest
#1Catriona Syme (U of T: University of Toronto)H-Index: 14
#2Stephanie Pelletier (U of T: University of Toronto)
Last. Zdenka Pausova (U of T: University of Toronto)H-Index: 36
view all 17 authors...
Life-long maintenance of brain health is important for the prevention of cognitive impairment in older age. Low-grade peripheral inflammation associated with excess visceral fat (VF) may influence brain structure and function. Here we examined (i) if this type of inflammation is associated with altered white-matter (WM) microstructure and lower cognitive functioning in adolescents, and (ii) if recently identified circulating glycerophosphocholines (GPCs) can index this type of inflammation and a...
Source
#1Jean Shin (U of T: University of Toronto)H-Index: 6
#2Leon French (U of T: University of Toronto)H-Index: 14
Last. Tomáš PausH-Index: 86
view all 10 authors...
11 CitationsSource
#1Marie-Ève Marchand-Krynski (UdeM: Université de Montréal)H-Index: 1
#2Anne-Marie Bélanger (Montreal Neurological Institute and Hospital)H-Index: 1
Last. LeonardGabriel (Montreal Neurological Institute and Hospital)H-Index: 35
view all 5 authors...
ABSTRACTThis study examined cognitive predictors of sequential motor skills in 215 children with dyslexia and/or attention deficit/hyperactivity disorder (ADHD). Visual working memory and math fluency abilities contributed significantly to performance of sequential motor abilities in children with dyslexia (N = 67), ADHD (N = 66) and those with a comorbid diagnosis (N = 82), generally without differentiation between groups. In addition, primary diagnostic features of each disorder, such as readi...
1 CitationsSource
#1Angelita Pui-Yee Wong (U of T: University of Toronto)H-Index: 4
#2Leon French (U of T: University of Toronto)H-Index: 14
Last. Tomáš PausH-Index: 86
view all 9 authors...
Abstract Age-related decreases in cortical thickness observed during adolescence may be related to fluctuations in sex and stress hormones. We examine this possibility by relating inter-regional variations in age-related cortical thinning (data from the Saguenay Youth Study) to inter-regional variations in expression levels of relevant genes (data from the Allen Human Brain Atlas); we focus on genes coding for glucocorticoid receptor (NR3C1), androgen receptor (AR), progesterone receptor (PGR), ...
9 CitationsSource
#1Catriona SymeH-Index: 14
#2Jean ShinH-Index: 6
Last. Zdenka PausovaH-Index: 36
view all 10 authors...
Hypertension is a leading cause of death. Sex differences in blood pressure (BP) and hypertension prevalence emerge during adolescence and remain throughout reproductive age. Sex differences in BP-underlying hemodynamics, i.e., in the relative contributions of stroke volume (SV), total peripheral resistance (TPR) and heart rate (HR) to BP, have not been investigated in these age categories in a population-based setting. We studied a cohort of 1,347 individuals, including 911 adolescents (12-18 y...
#1Nadine Parker (U of T: University of Toronto)H-Index: 1
#2Angelita Pui-Yee Wong (U of T: University of Toronto)H-Index: 4
Last. Tomáš PausH-Index: 86
view all 9 authors...
Income inequality is associated with poor health and social outcomes. Negative social comparisons and competition may involve the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes in underlying some of these complex inter-relationships. Here we investigate brain maturation, indexed by age-related decreases in cortical thickness, in adolescents living in neighborhoods with differing levels of income inequality and household income. We examine whether inter-regiona...
3 CitationsSource
Last. LeonardGabrielH-Index: 35
view all 5 authors...
5 CitationsSource
#1LeonardGabrielH-Index: 35
#2Yves LapierreH-Index: 1
Last. Alain PtitoH-Index: 40
view all 6 authors...
BackgroundMultiple sclerosis (MS) patients have central nervous system (CNS) lesions that may impede cognitive and sensorimotor function. Few rehabilitative therapies are available.ObjectivesThe objective of this paper is to study effects of noninvasive tongue stimulation using the Portable Neuromodulation Stimulator (PoNS™) combined with intensive cognitive and physical rehabilitation on working memory, gait, balance and concomitant changes in the brain.MethodsFourteen MS patients, seven each i...
9 CitationsSource
#1Catriona SymeH-Index: 14
#2Simon CzajkowskiH-Index: 1
Last. Zdenka PausovaH-Index: 36
view all 16 authors...
Background: Glycerophosphocholine (GPC) metabolites modulate atherosclerosis and thus risk for cardiovascular disease (CVD). Preclinical CVD may start during adolescence. Here, we used targeted serum lipidomics to identify a new panel of GPCs, and tested whether any of these GPCs are associated, in adolescence, with classical risk factors of CVD, namely excess visceral fat (VF), elevated blood pressure, insulin resistance, and atherogenic dyslipidemia. Methods: We studied a population-based samp...
Source
#1Catriona SymeH-Index: 14
#2Simon CzajkowskiH-Index: 1
Last. Zdenka PausovaH-Index: 36
view all 16 authors...
Background: Glycerophosphocholine (GPC) metabolites modulate atherosclerosis and thus risk for cardiovascular disease (CVD). Preclinical CVD may start during adolescence. Here, we used targeted serum lipidomics to identify a new panel of GPCs, and tested whether any of these GPCs are associated, in adolescence, with classical risk factors of CVD, namely excess visceral fat (VF), elevated blood pressure, insulin resistance, and atherogenic dyslipidemia. Methods: We studied a population-based samp...
Source
12345678910