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Derek Zieker
University of Tübingen
53Publications
17H-index
1,043Citations
Publications 53
Newest
Rami Archid3
Estimated H-index: 3
,
Carl Christoph Schneider2
Estimated H-index: 2
+ 3 AuthorsAlfred Königsrainer41
Estimated H-index: 41
Introduction Hemangiopericytoma (HPC) has been first described in 1942 by Stout as a tumor originating from the capillary surrounding pericytes. It is known to occur in any anatomical site, especially the extremities and retroperitoneum.
1 Citations Source Cite
Rami Archid3
Estimated H-index: 3
,
T Kratt10
Estimated H-index: 10
+ 5 AuthorsJörg Glatzle10
Estimated H-index: 10
Ectopic pancreas is a benign congenital abnormality, defined as pancreatic tissue that lacks anatomic or vascular continuity to the pancreas. An incidence of 0.55%-13% has been described in autopsy studies. Ectopic pancreas is most commonly found in the upper GI-Tract.
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Published on Oct 1, 2016in Journal of Hepatology 15.04
Markus W. Löffler8
Estimated H-index: 8
(University of Tübingen),
P. Anoop Chandran2
Estimated H-index: 2
(University of Tübingen)
+ 28 AuthorsHeiko Schuster12
Estimated H-index: 12
(University of Tübingen)
Background & Aims We report a novel experimental immunotherapeutic approach in a patient with metastatic intrahepatic cholangiocarcinoma. In the 5year course of the disease, the initial tumor mass, two local recurrences and a lung metastasis were surgically removed. Lacking alternative treatment options, aiming at the induction of anti-tumor T cells responses, we initiated a personalized multi-peptide vaccination, based on in-depth analysis of tumor antigens (immunopeptidome) and sequencing. Met...
15 Citations Source Cite
Published on Oct 1, 2015in International Journal of Surgery
Carl Christoph Schneider2
Estimated H-index: 2
(University of Tübingen),
Rami Archid3
Estimated H-index: 3
(University of Tübingen)
+ 9 AuthorsAlfred Königsrainer41
Estimated H-index: 41
(University of Tübingen)
Abstract Background and Objectives It can be assumed that PGK1 is involved in metastatic spread of gastric carcinomas. Furthermore PGK1 has a proven influence on the characteristics of tumor stem cells. The presence of malignant stem cells, regarding treatment resistance and recurrence, is of considerable importance. We hypothesized that inhibition of PGK1 makes these cells more sensitive to chemotherapeutic agents and therefore mediates an overcome of the existing therapy resistance. Methods Al...
3 Citations Source Cite
Published on Dec 1, 2015in Anticancer Research 1.86
Katharina Schmidt6
Estimated H-index: 6
(University of Regensburg),
Christian Moser16
Estimated H-index: 16
(University of Regensburg)
+ 6 AuthorsSven A. Lang23
Estimated H-index: 23
(University of Regensburg)
Abstract To assess the efficacy of targeting fibroblast growth factor receptor (FGFR) with the pan-FGFR inhibitor BGJ398 in a gastric cancer (GC) model. Expression of FGFRs was determined in GC cell lines (KKLS, MKN-45, TMK-1). Impact of the FGFR inhibitor BGJ398 on growth, motility, signaling, expression of transcription factors and secretion of vascular endothelial growth factor-A (VEGFA) was determined in vitro. Results were validated in subcutaneous tumor models. In vitro, FGFR inhibition wa...
6 Citations Source Cite
Published on Apr 1, 2015in International Surgery 0.58
Tobias Meile13
Estimated H-index: 13
,
Derek Zieker17
Estimated H-index: 17
+ 1 AuthorsJörg Glatzle10
Estimated H-index: 10
To perform stress-free recording of gastrointestinal motility in rats with strain gauge transducers, telemetry equipment had to be developed. We developed, programmed, and tested a new telemetry device that records gastrointestinal motility in freely moving rats using strain gauge transducers. The device can collect and transmit data in freely moving rats. Data are received and stored for later analysis with a regular PC. Linear calibration curves were obtained for the strain gauge transducers u...
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Published on Mar 30, 2015in PLOS ONE 2.77
Fabian Stuby9
Estimated H-index: 9
(University of Tübingen),
Stefan Döbele6
Estimated H-index: 6
(University of Tübingen)
+ 4 AuthorsDerek Zieker17
Estimated H-index: 17
(University of Tübingen)
Introduction This study was conducted according to GCP criteria as a prospective randomized cross-over study. The primary goal of the study was to determine clinical findings and patient satisfaction with postoperative treatment. 29 patients with a distal radius fracture that was surgically stabilized from volar and who met the inclusion criteria were enrolled over a 12-month period. Each patient randomly received either a dorsal plaster splint or a vacuum-fit flexible but blocked orthosis appli...
6 Citations Source Cite
Published on Feb 1, 2014in Surgery Today 2.50
Ingmar Königsrainer17
Estimated H-index: 17
(University of Tübingen),
Derek Zieker17
Estimated H-index: 17
(University of Tübingen)
+ 3 AuthorsStefan Beckert16
Estimated H-index: 16
(University of Tübingen)
Purpose In pancreatic cancer, the presence of peritoneal carcinomatosis (PC) precludes the possibility of a surgical cure, irrespective of the resectability of the primary tumor. However, peritoneal spread cannot be reliably detected radiographically during preoperative tumor staging.
8 Citations Source Cite
Published on May 1, 2014in Zeitschrift Fur Gastroenterologie 1.61
F. Eisner1
Estimated H-index: 1
(University of Tübingen),
M Küper15
Estimated H-index: 15
+ 3 AuthorsJörg Glatzle15
Estimated H-index: 15
(University of Tübingen)
Introduction: Patients with Crohn’s disease [CD] carry an 80 − 90 % lifetime risk of undergoing surgery. Many of these patients are on immunosuppressive medication at the time of surgery. The aim of this study was to evaluate the effect of immunosuppression on the surgical outcome in CD patients. Methods: We retrospectively analyzed 484 consecutive abdominal operations for CD from 1995 to 2008 for surgical complications. Results: A total of 241 operations (= 49.8 %) were performed under perioper...
2 Citations Source Cite
Published on Mar 1, 2013in Journal of Orthopaedic Trauma 2.46
Atesch Ateschrang10
Estimated H-index: 10
,
Dirk Albrecht11
Estimated H-index: 11
+ 3 AuthorsDerek Zieker17
Estimated H-index: 17
Objectives: To evaluate adjunctive compression plating leaving the previously unreamed inserted intramedullary nail (URIMN) in situ for treating a resultant diaphyseal tibial nonunion. Design: Retrospective study. Setting: Level 1 trauma center (University Hospital). Patients/Participants: Patients treated by URIMN for diaphyseal tibial fractures that developed an aseptic hypertrophic nonunion. Intervention: Dynamization of the nail and compression plating leaving the URIMN in situ. Main Outcome...
10 Citations Source Cite
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