Publications 112
#1AnneWSRutjesH-Index: 42
#2David A DentonH-Index: 2
Last.Jenny McCleeryH-Index: 12
view all 12 authors...
1 CitationsSource
#1Chiara TrevisiolH-Index: 6
#2Michela Cinquini (Mario Negri Institute for Pharmacological Research)H-Index: 15
Last.AnneWSRutjes (University of Bern)H-Index: 42
view all 5 authors...
Background The use of systematic review methods are widely recognized to be essential in the development of recommendations in clinical practice guidelines to prove their trustworthiness. The objective of this study was to assess the use of systematic search methods by authors of guidelines published in the oncology field.
#1Marcello Di Nisio (UvA: University of Amsterdam)H-Index: 30
#2Nick van Es (UvA: University of Amsterdam)H-Index: 17
Last.Ettore PorrecaH-Index: 28
view all 14 authors...
The long-term performance of prediction scores for venous thromboembolism (VTE) in cancer patients has been poorly investigated. We evaluated the discriminatory performance of the Khorana, PROTECHT, CONKO, and ONKOTEV scores for the first 3-6 months and for 12 months, and re-assessed scores after 3-6 months to determine the influence of variations in patients' risk classification on performance. Retrospective cohort of ambulatory patients with active cancer who were scheduled to receive first or...
#1Karine Toupin April (U of O: University of Ottawa)H-Index: 10
#2Jacinthe Bisaillon (Children's Hospital of Eastern Ontario)H-Index: 1
Last.Peter TugwellH-Index: 116
view all 11 authors...
1 CitationsSource
#1Monica HultcrantzH-Index: 13
#2Reem A. Mustafa (McMaster University)H-Index: 30
Last.Holger J. Schünemann (McMaster University)H-Index: 109
view all 19 authors...
Abstract Objective The objective of the study was to clarify how the Grading of Recommendations Assessment, Development and Evaluation (GRADE) concept of certainty of evidence applies to certainty ratings of test accuracy. Study Design and Setting After initial brainstorming with GRADE Working Group members, we iteratively refined and clarified the approaches for defining ranges when assessing the certainty of evidence for test accuracy within a systematic review, health technology assessment, o...
#1Nicola J. Gates (UNSW: University of New South Wales)H-Index: 13
#2Robin W.M. Vernooij (Cochrane Collaboration)H-Index: 12
Last.AnneWSRutjes (University of Bern)H-Index: 42
view all 7 authors...
BACKGROUND The number of people living with dementia is increasing rapidly. Clinical dementia does not develop suddenly, but rather is preceded by a period of cognitive decline beyond normal age-related change. People at this intermediate stage between normal cognitive function and clinical dementia are often described as having mild cognitive impairment (MCI). Considerable research and clinical efforts have been directed toward finding disease-modifying interventions that may prevent or delay p...
6 CitationsSource
#1Nicola J. Gates (UNSW: University of New South Wales)H-Index: 13
#2AnneWSRutjes (University of Bern)H-Index: 42
Last.Robin W.M. Vernooij (Cochrane Collaboration)H-Index: 12
view all 8 authors...
BACKGROUND Increasing age is associated with a natural decline in cognitive function and is also the greatest risk factor for dementia. Cognitive decline and dementia are significant threats to independence and quality of life in older adults. Therefore, identifying interventions that help to maintain cognitive function in older adults or to reduce the risk of dementia is a research priority. Cognitive training uses repeated practice on standardised exercises targeting one or more cognitive doma...
5 CitationsSource
#1Holger J. SchünemannH-Index: 109
#2Reem A. Mustafa (University of Birmingham)H-Index: 30
Last.Gordon H. Guyatt (McMaster University)H-Index: 201
view all 22 authors...
Abstract Objectives This article describes the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group's framework of moving from test accuracy to patient or population-important outcomes. We focus on the common scenario when studies directly evaluating the effect of diagnostic and other tests or strategies on health outcomes are not available or are not providing the best available evidence. Study Design and Setting Using practical examples, we explored how guide...
3 CitationsSource
#1Christina Raae Hansen (UCC: University College Cork)H-Index: 3
#2Denis O'Mahony (UCC: University College Cork)H-Index: 40
Last.Stephen Byrne (UCC: University College Cork)H-Index: 28
view all 11 authors...
AIMS Deprescribing interventions safely and effectively optimise medication use in older people. However, questions remain about which componentsof interventions are key to effectively reduce inappropriate medication use. This systematic review examines the behaviour change techniques (BCTs) of deprescribing interventions and summarises intervention effectiveness on medication use and inappropriate prescribing. METHODS MEDLINE, EMBASE, Web of Science and Academic Search Complete and grey literat...
2 CitationsSource
#1Juhani Knuuti (TYKS: Turku University Hospital)H-Index: 85
#2Haitham Ballo (TYKS: Turku University Hospital)H-Index: 2
Last.William Wijns (National University of Ireland, Galway)H-Index: 102
view all 10 authors...
Aims To determine the ranges of pre-test probability (PTP) of coronary artery disease (CAD) in which stress electrocardiogram (ECG), stress echocardiography, coronary computed tomography angiography (CCTA), single-photon emission computed tomography (SPECT), positron emission tomography (PET), and cardiac magnetic resonance (CMR) can reclassify patients into a post-test probability that defines (>85%) or excludes (<15%) anatomically (defined by visual evaluation of invasive coronary angiography ...
20 CitationsSource