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Laura E. Edsberg
Daemen College
37Publications
13H-index
784Citations
Publications 37
Newest
Published on Jun 1, 2018in Genomics, Proteomics & Bioinformatics
Erin L. Crowgey2
Estimated H-index: 2
(Alfred I. duPont Hospital for Children),
Jennifer T. Wyffels2
Estimated H-index: 2
(University of Delaware)
+ 2 AuthorsLaura E. Edsberg13
Estimated H-index: 13
(Daemen College)
Abstract Heterotopic ossification (HO) refers to the abnormal formation of bone in soft tissue. Although some of the underlying processes of HO have been described, there are currently no clinical tests using validated biomarkers for predicting HO formation. As such, the diagnosis is made radiographically after HO has formed. To identify potential and novel biomarkers for HO, we used isobaric tags for relative and absolute quantitation (iTRAQ) and high-throughput antibody arrays to produce a sem...
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Published on Dec 1, 2017in Journal of Orthopaedic Surgery and Research 1.61
Laura E. Edsberg13
Estimated H-index: 13
(Daemen College),
Erin L. Crowgey2
Estimated H-index: 2
(Alfred I. duPont Hospital for Children)
+ 1 AuthorsJennifer T. Wyffels2
Estimated H-index: 2
(University of Delaware)
Background Heterotopic ossification (HO) is a significant problem for wounded warriors surviving high-energy blast injuries; however, currently, there is no biomarker panel capable of globally characterizing, diagnosing, and monitoring HO progression. The aim of this study was to identify biomarkers for HO using proteomic techniques and blood serum.
2 Citations Source Cite
Published on Jan 1, 2016in Journal of Wound Ostomy and Continence Nursing 1.59
Laura E. Edsberg13
Estimated H-index: 13
(Daemen College),
Joyce Black14
Estimated H-index: 14
+ 3 AuthorsMary Sieggreen7
Estimated H-index: 7
(Harper University Hospital)
Our understanding of pressure injury etiology and development has grown in recent years through research, clinical expertise, and global interdisciplinary expert collaboration. Therefore, the National Pressure Ulcer Advisory Panel (NPUAP) has revised the definition and stages of pressure injury. The revision was undertaken to incorporate the current understanding of the etiology of pressure injuries, as well as to clarify the anatomical features present or absent in each stage of injury. An NPUA...
44 Citations Source Cite
Published on Jul 1, 2015in Journal of Spinal Cord Medicine 1.88
Laura E. Edsberg13
Estimated H-index: 13
(Daemen College),
Jennifer T. Wyffels8
Estimated H-index: 8
(Daemen College)
+ 2 AuthorsPamela Houghton4
Estimated H-index: 4
(University of Western Ontario)
AbstractObjectiveTo determine whether the biochemistry of chronic pressure ulcers differs between patients with and without chronic spinal cord injury (SCI) through measurement and comparison of the concentration of wound fluid inflammatory mediators, growth factors, cytokines, acute phase proteins, and proteases.DesignSurvey.SettingTertiary spinal cord rehabilitation center and skilled nursing facilities.ParticipantsTwenty-nine subjects with SCI and nine subjects without SCI (>18 years) with at...
4 Citations Source Cite
Published on Jan 1, 2014in Journal of Wound Ostomy and Continence Nursing 1.59
Laura E. Edsberg13
Estimated H-index: 13
,
Diane Langemo22
Estimated H-index: 22
+ 2 AuthorsMargaret Goldberg10
Estimated H-index: 10
51 Citations Source Cite
Published on Jan 1, 2013
Kehua Zhou7
Estimated H-index: 7
,
Michael S. Brogan7
Estimated H-index: 7
+ 1 AuthorsLaura E. Edsberg13
Estimated H-index: 13
In East Asian countries, oriental medicine (OM) has been used for thousands of years to manage a wide variety of chronic wounds, but in western countries the role of OM in wound care remains to be established. To summarize current practices and available evidence of OM in the management of chronic wounds, a search of Chinese and English databases was conducted and summarized with an emphasis on randomized controlled trials, clinical trials, and meta-analyses of topical and systemic OM treatments...
Published on Jan 1, 2013in Ostomy Wound Management 0.99
Kehua Zhou7
Estimated H-index: 7
(Daemen College),
Michael S. Brogan7
Estimated H-index: 7
+ 2 AuthorsLaura E. Edsberg13
Estimated H-index: 13
In East Asian countries, oriental medicine (OM) has been used for thousands of years to manage a wide variety of chronic wounds, but in western countries the role of OM in wound care remains to be established. To summarize current practices and available evidence of OM in the management of chronic wounds, a search of Chinese and English databases was conducted and summarized with an emphasis on randomized controlled trials, clinical trials, and meta-analyses of topical and systemic OM treatments...
1 Citations
Published on May 1, 2012in Wound Repair and Regeneration 2.95
Laura E. Edsberg13
Estimated H-index: 13
(Daemen College),
Jennifer T. Wyffels8
Estimated H-index: 8
(Daemen College)
+ 1 AuthorsKristin M. Fries6
Estimated H-index: 6
(Daemen College)
Analysis of the proteomic profile of pressure ulcers over time is a critical step in the identification of biomarkers of healing or nonhealing in pressure ulcers. The wound fluid from 32 subjects with 42 pressure ulcers was evaluated over 6 weeks at 15 time points. Samples specific to both the interior and the periphery of the wound bed were collected. Antibody screening arrays, isobaric tags for relative and absolute quantitation with mass spectrometry and multiplexed microarrays were used to c...
27 Citations Source Cite
Published on Oct 1, 2011in Advances in Skin & Wound Care 1.38
Jennifer T. Wyffels8
Estimated H-index: 8
,
Laura E. Edsberg13
Estimated H-index: 13
ABSTRACT To describe the temporal relationship between the quantity of granulation tissue in a chronic pressure ulcer (PrU) and its clinical outcome. Study participants were seen on days 0, 1, 2, 3, 4, 7, 8, 9, 10, 11, 14, 21, 28, 35, and 42. On each visit, the wounds were digitally photographed with a 3-cm2 calibration target. Images were analyzed using VeV MD (version 1.1.14; VERG Inc, Winnipeg, Manitoba, Canada) and Adobe Photoshop CS3 Extended (version 10.0.1; Adobe Systems Inc, San Jose, Ca...
7 Citations Source Cite
Published on Jan 1, 2011in Journal of Oral and Maxillofacial Surgery 1.78
Megan M. Herr1
Estimated H-index: 1
(Daemen College),
Kristin M. Fries6
Estimated H-index: 6
(Daemen College)
+ 1 AuthorsLaura E. Edsberg13
Estimated H-index: 13
(Daemen College)
Purpose The purpose of this study was to identify protein markers present in subjects with temporomandibular joint disorders (TMDs) and clicking compared with the levels in controls. Materials and Methods This was a pilot case-control study, and we report the preliminary results. Samples of joint aspirate collected from patients with TMDs and controls who had undergone surgery for a problem other than TMDs were analyzed using isobaric tags for relative and absolute quantitation (iTRAQ) and bioti...
14 Citations Source Cite
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