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Marko Gerić
ChemistryGenotoxicityComet assayMicronucleus testBiology
60Publications
10H-index
283Citations
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Publications 67
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AbstractAn adequate level of low molecular weight thiols (LMW-SH, especially glutathione (GSH)) protects cellular macromolecules against toxic agents, and is used as a sensitive biomarker of exposu...
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#1Goran GajskiH-Index: 16
#2Marko GerićH-Index: 10
Last. Alica PizentH-Index: 14
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Abstract This study proposes the application of the comet assay for the evaluation of DNA damage from frozen human whole blood samples that could be readily used in human biomonitoring and epidemiological studies. It was done on simply frozen whole blood samples collected from male volunteers (N = 60) aliquoted in small volumes and stored at −80 °C without the addition of cryopreservatives for a period of 5 years. To test the applicability of the alkaline comet assay for the evaluation of DNA da...
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#1Marko GerićH-Index: 10
#2Goran GajskiH-Index: 16
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#2Marko GerićH-Index: 10
Last. Jadranka FreceH-Index: 12
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#2Marko GerićH-Index: 10
Last. Jadranka FreceH-Index: 12
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Abstract Imatinib mesylate (IM) is the first developed protein kinase inhibitor and recently it has topped consumption rates among targeted and total anticancer drugs. Although there are indications that IM possesses cyto/genotoxic activities against normal non-target cells as well, there is a lack of information regarding the underlying mechanism involved in those actions. Therefore, we aimed to evaluate the response of human circulating blood cells towards oxidative stress after IM treatment (...
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#2Marko GerićH-Index: 10
Last. Ana-Marija DomijanH-Index: 25
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Abstract Sodium copper chlorophyllin (CHL) is a food colorant that exhibits many beneficial properties, including potential for use in radiotherapy. Nevertheless, genotoxicity studies investigating radioprotective properties against γ-radiation on human cells are rather scarce. The aim of this study was to assess the cytotoxicity, genotoxicity and induction of malondialdehyde formation on CHL pre-treated whole blood cells after an absorbed dose of 5 Gy γ-radiation. Irradiated whole blood cells p...
1 CitationsSource
#1Marko GerićH-Index: 10
#2Jelena Popić (University of Zagreb)H-Index: 2
Last. Vera Garaj-VrhovacH-Index: 24
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Abstract Interventional radiology unit workers represent one of the occupationally most exposed populations to low-dose ionizing radiation. Since there are many uncertainties in research of doses below 100 mSv, this study attempted to evaluate DNA damage levels in chronically exposed personnel. The study group consisted of 24 subjects matched with a control population by the number of participants, age, gender ratio, active smoking status, the period of blood sampling, and residence. Based on re...
3 CitationsSource
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