Jerka Dumić
University of Zagreb
ChemistryGalectin-3BiochemistryBiologyCell biology
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Publications 80
#1Mirna FlögelH-Index: 12
#2Jerka DumićH-Index: 13
Last. Sandra ŠuprahaH-Index: 2
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#1Antonija PerovićH-Index: 3
#2Marko ŽarakH-Index: 1
Last. Jerka Dumić (University of Zagreb)H-Index: 13
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PURPOSE Previous studies have shown an increase in erythrocyte lipid peroxidation and a decrease in red blood cell (RBC) count, hemoglobin, and hematocrit after only one recreational scuba diving session. The aim of this study was to examine the effect of repetitive scuba diving on RBC parameters and erythropoiesis. METHODS Divers (N = 14) conducted one dive per week over 5 weeks at a depth of 20-30 m for 30 min. For measuring RBC parameters, erythropoietin, iron, and ferritin, blood samples wer...
#1Marko ŽarakH-Index: 1
#2Antonija PerovićH-Index: 3
Last. Jerka Dumić (University of Zagreb)H-Index: 13
view all 5 authors...
To understand better the adaptation response of the cardiovascular system (CVS) to self-contained underwater breathing apparatus (SCUBA) diving, Galectin-3 (Gal-3) and specific CVS biomarkers were measured in plasma of 16 male recreational divers before and after (30 min, 3 and 6 h) diving (total time of 30 min at 30 m depth) undertaken a after long non-dive period. The one-time SCUBA dive caused a significant increase in Gal-3, N-terminal prohormone of brain natriuretic peptide (NT-proBNP), hig...
1 CitationsSource
#1Anita Somborac-Bačura (University of Zagreb)H-Index: 6
#2Lada Rumora (University of Zagreb)H-Index: 15
Last. Tihana Žanić-Grubišić (University of Zagreb)H-Index: 10
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NEW FINDINGS: What is the central question of this study? What is the effect of cigarette smoke on cell death, oxidative damage, expression of heat shock proteins (HSPs) and activation of mitogen-activated protein kinases (MAPKs) in A549 alveolar epithelial cells? What is the main finding and its importance? Cigarette smoke induces cytotoxicity and oxidative damage to A549 cells, increases expression of different HSPs and activates MAPK signalling pathways. This could be related to inflammatory ...
6 CitationsSource
#1Marko SkelinH-Index: 4
#2Tomo LucijanićH-Index: 4
Last. Dario RahelićH-Index: 17
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Aim Hypothyroidism is a common clinical problem that is successfully treated with hormone substitutes in the form of levothyroxine (LT4). LT4 is a drug with a narrow therapeutic index and is usually administered by strict rules, standardly at least half an hour before breakfast. The aim of this study was to investigate a possible effect of different timings of administration on thyroid function status and lipid profile.
4 CitationsSource
#1Antonija PerovićH-Index: 3
#2Sandra SobočanecH-Index: 12
Last. Jerka Dumić (University of Zagreb)H-Index: 13
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AbstractThe aim of this study was to examine the effects of scuba diving on oxidative damage markers in erythrocytes and plasma, antioxidant system in peripheral blood mononuclear cells (PBMCs), as well as sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) gene expressions in recreational divers after a winter nondive period (at least 5 months). For that purpose, 17 male recreational divers performed an immersion at a depth of 30 m for 30 min. Blood samples were collected immediately before and after divin...
3 CitationsSource
#1Milica Miljković (University of Belgrade)H-Index: 7
#2Aleksandra Stefanović (University of Belgrade)H-Index: 18
Last. Jelena Kotur-Stevuljevic (University of Belgrade)H-Index: 20
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: Inflammation, apoptosis and extracellular remodeling play significant roles in cardiovascular disease (CVD) underlying the major causes of mortality in renal patients. In 19 pre-dialysis patients, 21 dialysis patients and 20 control subjects, the concentrations of pentraxin-3, galectin-3, MMP-9 and TIMP-1 were determined by ELISA. CVD risk was calculated according to the Framingham risk score algorithm. Pentraxin-3 was increased in renal patients compared to healthy controls (p<0.001). In cont...
2 CitationsSource
#1Antonija PerovićH-Index: 3
#2Nora NikolacH-Index: 17
Last. Jerka Dumić (University of Zagreb)H-Index: 13
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IntroductionScuba diving represents a combination of exercise and changes in environmental conditions. This study aimed to evaluate changes in haemato
7 CitationsSource
#2Sanja DabelićH-Index: 9
Last. Jerka DumićH-Index: 13
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#1Jerka DumićH-Index: 13
#2Sanja DabelićH-Index: 9
Last. Karmela BarišićH-Index: 13
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Inhibition of Hsp90 is a promising therapeutic approach with clinical relevance for treatment of specific tumour types since both Hsp90 homologous (Hsp90α and Hsp90β) account for maturation and functional stability of a plethora of polypeptides (Hsp90 client proteins), including many proteins involved in tumorigenesis (e.g. antiapoptotic and signaltransduction proteins, transcription factors, Tyrkinase receptors, etc.). Galectin3, a βgalactoside lectin is a multifunctional protein, ubiquitously ...