Ellen F. Crain
Albert Einstein College of Medicine
SurgeryIntensive care medicineAsthmaEmergency departmentMedicine
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Publications 117
#1Philip J. Landrigan (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 68
#2Joseph M. Braun (Brown University)H-Index: 32
Last. Robert O. Wright (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 56
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Abstract Background Environmental exposures contribute to multiple diseases in children; yet, few pediatricians have training in pediatric environmental health (PEH), and few academic health centers have PEH expertise. To build national capacity in PEH, the Academic Pediatric Association (APA) launched a professional development program that since 2002 has encouraged the establishment of post-residency/post-doctoral training programs, supported a special interest group, and convened an annual me...
#1Nathan Kuppermann (UC Davis: University of California, Davis)H-Index: 46
#2Peter S. Dayan (Columbia University)H-Index: 33
Last. Prashant Mahajan (UM: University of Michigan)H-Index: 27
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Importance In young febrile infants, serious bacterial infections (SBIs), including urinary tract infections, bacteremia, and meningitis, may lead to dangerous complications. However, lumbar punctures and hospitalizations involve risks and costs. Clinical prediction rules using biomarkers beyond the white blood cell count (WBC) may accurately identify febrile infants at low risk for SBIs. Objective To derive and validate a prediction rule to identify febrile infants 60 days and younger at low ri...
10 CitationsSource
#1Prashant Mahajan (UM: University of Michigan)H-Index: 27
#2Lorin R. Browne (Children's Hospital of Wisconsin)H-Index: 1
Last. Kathleen Lillis (Women & Children's Hospital of Buffalo)H-Index: 17
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Objective To determine the risk of serious bacterial infections (SBIs) in young febrile infants with and without viral infections. Study design Planned secondary analyses of a prospective observational study of febrile infants 60 days of age or younger evaluated at 1 of 26 emergency departments who did not have clinical sepsis or an identifiable site of bacterial infection. We compared patient demographics, clinical, and laboratory findings, and prevalence of SBIs between virus-positive and viru...
4 CitationsSource
#1Elizabeth C. Powell (Children's Memorial Hospital)H-Index: 24
#2Prashant Mahajan (UM: University of Michigan)H-Index: 1
Last. Kathleen LillisH-Index: 17
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Study objective To describe the current epidemiology of bacteremia in febrile infants 60 days of age and younger in the Pediatric Emergency Care Applied Research Network (PECARN). Methods We conducted a planned secondary analysis of a prospective observational study of febrile infants 60 days of age and younger presenting to any of 26 PECARN emergency departments (2008 to 2013) who had blood cultures obtained. We excluded infants with significant comorbidities or critically ill appearance. The p...
15 CitationsSource
#1Michael Gorn (Albert Einstein College of Medicine)H-Index: 3
#2Sergey Kunkov (SBU: Stony Brook University)H-Index: 4
Last. Ellen F. Crain (Albert Einstein College of Medicine)H-Index: 38
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Objective The objective was to describe a novel ultrasound-assisted lumbar puncture (UALP) technique and to compare it to standard lumbar puncture (SLP) technique in infants. Methods A prospective, randomized, controlled study in infants 60 days old and younger undergoing a lumbar puncture (LP) in a pediatric emergency department. Patients with a spinal anomaly or ventriculoperitoneal shunt were excluded. Eligible infants were randomized to UALP or SLP. A spinal sonogram was performed on all pat...
10 CitationsSource
#1James A. MeltzerH-Index: 6
#2Sergey KunkovH-Index: 4
Last. Ellen F. CrainH-Index: 38
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The aim of this study was to assess whether increased time from emergency department (ED) triage to appendectomy is associated with a greater risk of children developing appendiceal perforation. We performed a multicenter retrospective cohort study of children younger than 18 years hospitalized with appendicitis. To avoid enrolling patients who had perforated prior to ED arrival, we included only children who had a computed tomography (CT) scan demonstrating nonperforated appendicitis. Time to a...
5 CitationsSource
#1Prashant Mahajan (WSU: Wayne State University)H-Index: 27
#2Nathan Kuppermann (University of California, Berkeley)H-Index: 46
Last. Octavio Ramilo (OSU: Ohio State University)H-Index: 54
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Importance Young febrile infants are at substantial risk of serious bacterial infections; however, the current culture-based diagnosis has limitations. Analysis of host expression patterns (“RNA biosignatures”) in response to infections may provide an alternative diagnostic approach. Objective To assess whether RNA biosignatures can distinguish febrile infants aged 60 days or younger with and without serious bacterial infections. Design, Setting, and Participants Prospective observational study ...
69 CitationsSource
#1Ellen F. Crain (Albert Einstein College of Medicine)H-Index: 38
From the Departments of Pediatrics and Emergency Medicine, Albert Einstein College of Medicine, Bronx, NY The author declares that she has no conflict of interest. Address correspondence to Ellen F. Crain, MD, PhD, Department of Pediatrics, Jacobi Medical Center, Albert Einstein College of Medicine, 1400 Pelham Pkwy S, J1W20, Bronx, NY 10461 (e-mail: Received for publication September 19, 2013; accepted September 19, 2013.
#1William CrainH-Index: 2
#2Ellen F. CrainH-Index: 38
#1Devin S. GrossmanH-Index: 1
#2Sergey KunkovH-Index: 4
Last. Ellen F. CrainH-Index: 38
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