Match!
Laura Fejerman
University of California, San Francisco
68Publications
16H-index
845Citations
Publications 68
Newest
#1Joshua D. Hoffman (UCSF: University of California, San Francisco)H-Index: 8
#2Laura Fejerman (UCSF: University of California, San Francisco)H-Index: 16
Last.Elad Ziv (UCSF: University of California, San Francisco)H-Index: 51
view all 22 authors...
Background Breast cancer is a partially heritable trait and genome-wide association studies (GWAS) have identified over 180 common genetic variants associated with breast cancer. We have previously performed breast cancer GWAS in Latinas and identified a strongly protective single nucleotide polymorphism (SNP) at 6q25, with the protective minor allele originating from indigenous American ancestry. Here we report on fine mapping of the 6q25 locus in an expanded sample of Latinas.
#1Yiwey Shieh (UCSF: University of California, San Francisco)H-Index: 7
#2Laura Fejerman (UCSF: University of California, San Francisco)H-Index: 16
Last.Susan L. Neuhausen (City of Hope National Medical Center)H-Index: 60
view all 0 authors...
#1Alice Guan (UCSF: University of California, San Francisco)
#2Daphne Y. Lichtensztajn (UCSF: University of California, San Francisco)
Last.Laura Fejerman (UCSF: University of California, San Francisco)H-Index: 16
view all 0 authors...
Background: This study uses a novel geographic approach to summarize the distribution of breast cancer in San Francisco and aims to identify the neighborhoods and racial/ethnic groups that are disproportionately affected by this disease. Methods: Nine geographic groupings were newly defined based on racial/ethnic composition and neighborhood socioeconomic status. Distribution of breast cancer cases from the Greater Bay Area Cancer Registry in these zones were examined. Multivariable logistic reg...
Breast cancer is the most common cancer in Latina women. Although they have a lower incidence of the disease when compared to other population groups such as Non-Hispanic White and Afro-American women, some studies have shown that Latina women have a higher risk of mortality when compared to Non-Hispanic White women. This phenomenon can be explained in part by the higher prevalence of aggressive subtypes in Latina women, particularly, the triple negative. Such differences in breast cancer intrin...
#1Yiwey Shieh (University of California, Berkeley)H-Index: 7
#2L. Fejerman (University of California, Berkeley)
Last.Susan L. Neuhausen (Beckman Research Institute)H-Index: 60
view all 23 authors...
Background: Over 180 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility have been identified; these SNPs can be combined into polygenic risk scores (PRS) to predict breast cancer risk. Since most SNPs were identified in predominantly European populations, little is known about the performance of PRS in non-Europeans. We tested the performance of a 180-SNP PRS in Latinas, a large ethnic group with variable levels of Indigenous American, European, and African ances...
12345678