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Maria Chondronikola
Washington University in St. Louis
42Publications
13H-index
1,042Citations
Publications 42
Newest
#1Takeshi Yoneshiro (UCSF: University of California, San Francisco)H-Index: 21
#2Qiang Wang (UCSF: University of California, San Francisco)H-Index: 3
Last.Shingo Kajimura (UCSF: University of California, San Francisco)H-Index: 43
view all 36 authors...
Branched-chain amino acid (BCAA; valine, leucine and isoleucine) supplementation is often beneficial to energy expenditure; however, increased circulating levels of BCAA are linked to obesity and diabetes. The mechanisms of this paradox remain unclear. Here we report that, on cold exposure, brown adipose tissue (BAT) actively utilizes BCAA in the mitochondria for thermogenesis and promotes systemic BCAA clearance in mice and humans. In turn, a BAT-specific defect in BCAA catabolism attenuates sy...
#1Maria Chondronikola (UoA: National and Kapodistrian University of Athens)H-Index: 13
#2Lambros Sidossis (RU: Rutgers University)H-Index: 43
Abstract The recent re-discovery of brown adipose tissue (BAT) and even more recent discovery of the browning of white adipose tissue (WAT) in humans have generated intense scientific interest in the role of adipose tissue as potential target against obesity and its metabolic complications. The purpose of this review is to: i) critically evaluate the current evidence on the physiological significance of BAT and the browning of WAT in metabolic function in humans and ii) discuss factors that have...
#1Rabia Asghar (UTMB: University of Texas Medical Branch)H-Index: 1
#2Maria Chondronikola (UTMB: University of Texas Medical Branch)H-Index: 13
Last.Demidmaa TuvdendorjH-Index: 11
view all 15 authors...
#1Constantina Papoutsakis (UoA: National and Kapodistrian University of Athens)H-Index: 17
#2Eleni Papadakou (UoA: National and Kapodistrian University of Athens)H-Index: 1
Last.Kostas N. Priftis (UoA: National and Kapodistrian University of Athens)H-Index: 27
view all 8 authors...
Purpose Lifestyle (diet and physical activity) may increase asthma risk, but evidence in this area is lacking. The aims of the present study were to calculate an obesity-preventive lifestyle score comprising of eating and physical activity behaviors and investigate the overall effect of lifestyle on asthma in children.
#1Maria Chondronikola (Atkins)H-Index: 13
#2Faidon Magkos (Agency for Science, Technology and Research)H-Index: 43
Last.Samuel Klein (Atkins)H-Index: 87
view all 8 authors...
#1Maria Chondronikola (WashU: Washington University in St. Louis)H-Index: 13
#2Scott C. Beeman (WashU: Washington University in St. Louis)H-Index: 12
Last.Richard L. Wahl (WashU: Washington University in St. Louis)H-Index: 85
view all 3 authors...
Brown adipose tissue (BAT) is a recently rediscovered tissue in people that has shown promise as a potential therapeutic target against obesity and its metabolic abnormalities. Reliable non-invasive assessment of BAT volume and activity is critical to allow its importance in metabolic control to be evaluated. Positron emission tomography/computed tomography (PET/CT) in combination with 2-deoxy-2-[18 F]fluoroglucose administration is currently the most frequently used and most established method ...
#1Maria Chondronikola (UoA: National and Kapodistrian University of Athens)H-Index: 13
#2Scott C. Beeman (WashU: Washington University in St. Louis)H-Index: 12
Last.Richard L. Wahl (WashU: Washington University in St. Louis)H-Index: 85
view all 3 authors...
#1Maria Chondronikola (UTMB: University of Texas Medical Branch)H-Index: 13
#2Rabia Asghar (UTMB: University of Texas Medical Branch)H-Index: 1
Last.Demidmaa Tuvdendorj (UTMB: University of Texas Medical Branch)H-Index: 11
view all 15 authors...
Summary Background Circulating acyl-carnitines (acyl-CNTs) are associated with insulin resistance (IR) and type 2 diabetes (T2D) in both rodents and humans. However, the mechanisms whereby circulating acyl-CNTs are increased in these conditions and their role in whole-body metabolism remains unknown. The purpose of this study was to determine if, in humans, blood cells contribute in production of circulating acyl-CNTs and associate with whole-body fat metabolism. Methods and results Eight non-di...
#1Maria Chondronikola (UoA: National and Kapodistrian University of Athens)H-Index: 13
#2Lambros Sidossis (UTMB: University of Texas Medical Branch)H-Index: 43
The recent discovery of functional brown adipose tissue (BAT) in adults has stimulated intense interest for its therapeutic potential against obesity and its related metabolic conditions. Although rodent studies support the importance of brown and beige adipocytes in metabolic health, a smaller number of clinical investigations have examined their physiological significance in people. This chapter provides a critical overview of the published research regarding the metabolic role of BAT and the ...
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