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Hans-Christoph Diener
University of Duisburg-Essen
Publications 1228
Published on Dec 1, 2019
Hans-Christoph Diener94
Estimated H-index: 94
Armin J. Grau40
Estimated H-index: 40
Stephan Baldus59
Estimated H-index: 59
Interventional patent foramen ovale (PFO) closure should be performed in patients aged 16 to 60 years (after extensive neurological and cardiological diagnostic work-up) with a history of cryptogenic ischaemic stroke and patent foramen ovale, with moderate or extensive right-to-left shunt.
Published on Jun 1, 2019in Lancet Neurology 28.75
Hans-Christoph Diener94
Estimated H-index: 94
David William Dodick66
Estimated H-index: 66
(Mayo Clinic)
+ 6 AuthorsTodd J. Schwedt27
Estimated H-index: 27
(Mayo Clinic)
Summary Regular or frequent use of analgesics and acute antimigraine drugs can increase the frequency of headache, and induce the transition from episodic to chronic headache or medication overuse headache. The 1-year prevalence of this condition in the general population is between 1% and 2%. Medication overuse headache is more common in women and in people with comorbid depression, anxiety, and other chronic pain conditions. Treatment of medication overuse headache has three components. First,...
Hans-Christoph Diener94
Estimated H-index: 94
Christian Gerloff63
Estimated H-index: 63
+ -3 AuthorsGötz Thomalla37
Estimated H-index: 37
Victor J. Del Brutto12
Estimated H-index: 12
(UM: University of Miami),
Seemant Chaturvedi (UMB: University of Maryland, Baltimore)+ -3 AuthorsRalph L. Sacco123
Estimated H-index: 123
(UM: University of Miami)
Abstract Stroke survivors carry a high risk of recurrence. Antithrombotic medications are paramount for secondary prevention and thus crucial to reduce the overall stroke burden. Appropriate antithrombotic agent selection should be based on the best understanding of the physiopathological mechanism that led to the initial ischemic injury. Antiplatelet therapy is preferred for lesions characterized by atherosclerosis and endothelial injury, whereas anticoagulant agents are favored for cardiogenic...
Published in The Lancet 59.10
Michel D. Ferrari74
Estimated H-index: 74
(LEI: Leiden University),
Hans-Christoph Diener94
Estimated H-index: 94
+ -3 AuthorsMelissa Grozinski-Wolff1
Estimated H-index: 1
Summary Background Antibodies targeting calcitonin gene-related peptide (CGRP) or its receptor have shown efficacy in the prevention of migraine attacks. We investigated the efficacy and tolerability of fremanezumab, a fully humanised CGRP antibody, in patients with migraine who had previously not responded to two to four classes of migraine preventive medications. Methods The randomised, double-blind, placebo-controlled, parallel-group, phase 3b FOCUS trial was done at 104 sites (including hosp...
Published on May 23, 2019in Stroke 6.05
Natan M. Bornstein41
Estimated H-index: 41
(TAU: Tel Aviv University),
Jeffrey L. Saver99
Estimated H-index: 99
(UCLA: University of California, Los Angeles)
+ 341 AuthorsCarlos A. Molina (Hebron University)
Published on May 21, 2019in Cephalalgia 4.44
David William Dodick66
Estimated H-index: 66
(Mayo Clinic),
Stephen D. Silberstein78
Estimated H-index: 78
+ 3 AuthorsHans-Christoph Diener94
Estimated H-index: 94
BackgroundThe Phase 3 REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) trials demonstrated efficacy/tolerability of onabotulinumtoxinA for headache prevention in adults with chronic migraine. This post hoc analysis assessed time of onset of onabotulinumtoxinA after the first treatment in total and responder populations and consistency weekly through five treatment cycles.MethodsIn the 24-week, double-blind, placebo-controlled phase of PREEMPT, individuals were randomized 1:1 to onabotu...
Published on Jul 1, 2019in Stroke 6.05
Jacoba P. Greving16
Estimated H-index: 16
Hans-Christoph Diener94
Estimated H-index: 94
+ 9 AuthorsJean-Louis Mas51
Estimated H-index: 51
Background and Purpose— We assessed the efficacy and safety of antiplatelet agents after noncardioembolic stroke or transient ischemic attack and examined how these vary according to patients’ demo...