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Thomas Frauenfelder
University of Zurich
RadiologyPathologyCardiologyAortic valveMedicine
172Publications
26H-index
2,050Citations
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Publications 181
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Abstract Purpose To evaluate a deep learning based image analysis software for the detection and localization of distal radius fractures. Method A deep learning system (DLS) was trained on 524 wrist radiographs (166 showing fractures). Performance was tested on internal (100 radiographs, 42 showing fractures) and external test sets (200 radiographs, 100 showing fractures). Single and combined views of the radiographs were shown to DLS and three readers. Readers were asked to indicate fracture lo...
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#1Matthias Eberhard (UZH: University of Zurich)H-Index: 4
#2Christian Blüthgen (UZH: University of Zurich)H-Index: 2
Last. Katharina Martini (UZH: University of Zurich)H-Index: 7
view all 6 authors...
Objectives To assess the effect of vertical off-centering in tube current modulation (TCM) on effective-dose and image-noise in reduced-dose (RD) chest-CT. Methods One-hundred consecutive patients (36 female; mean age 56 years) were scanned on a 192-slice CT scanner with a standard-dose (ND) and a RD chest-CT protocol using tube current modulation. Image-noise was evaluated by placing circular regions of interest in the apical, middle, and lower lung regions. Two independent readers evaluated im...
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Last. Magda Marcon (UZH: University of Zurich)H-Index: 8
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To evaluate the diagnostic performance of dynamic contrast-enhanced (DCE)–MRI in predicting malignancy after percutaneous biopsy diagnosis of atypical ductal hyperplasia (ADH). In this retrospective study, 68 lesions (66 women) with percutaneous biopsy diagnosis of ADH and pre-operative breast DCE-MRI performed between January 2016 and December 2017 were included. Two radiologists reviewed in consensus mammography, ultrasound, and MR images. The final diagnosis after surgical excision was used a...
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Last. Isabelle OpitzH-Index: 1
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We present the unusual case of a 25-year-old female with shortness of breath, concomitant cough and a palpable mass in the left lower neck. The patient underwent thoracotomy via clamshell incision to remove the mass of preoperative unknown aetiology. A preoperative biopsy was inconclusive. Histology surprisingly revealed a lipoblastoma. The patient is without evidence of tumour relapse after 60 months. The lipoblastoma is a neoplasm of the embryonic adipose tissue. Typically, it is seen in the e...
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#1Katharina MartiniH-Index: 7
Last. Thomas FrauenfelderH-Index: 26
view all 9 authors...
Rationale and Objectives To assess if vessel suppression (VS) improves nodule detection rate, interreader agreement, and reduces reading time in oncologic chest computed tomography (CT). Material and Methods One-hundred consecutive oncologic patients (65 male; median age 60y) who underwent contrast-enhanced chest CT were retrospectively included. For all exams, additional VS series (ClearRead CT, Riverrain Technologies, Miamisburg) were reconstructed. Two groups of three radiologists each with m...
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#1Nicole BergerH-Index: 7
#2Magda MarconH-Index: 8
Last. Andreas BossH-Index: 33
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OBJECTIVES The aim of this study was to describe our initial clinical experiences using a dedicated spiral breast computed tomography (B-CT) with a single photon-counting detector. MATERIALS AND METHODS This retrospective study was approved by the institutional review board. Examinations of 300 consecutive women undergoing B-CT were evaluated on reason of assignment for B-CT instead of mammography, detection rate of breast cancer, and quality criteria of data acquisition. Further evaluated perfo...
1 CitationsSource
#1Andrew G. Nicholson (NIH: National Institutes of Health)H-Index: 96
#2Jennifer L. Sauter (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 8
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Abstract Introduction Molecular and immunologic breakthroughs are transforming the management of thoracic cancer, although advances have not been as marked for malignant pleural mesothelioma (MPM) where pathologic diagnosis has been essentially limited to three histologic subtypes. Methods A multidisciplinary group (pathologists, molecular biologists, surgeons, radiologists and oncologists), sponsored by EURACAN/IASLC met in 2018, to critically review the current classification. Results Recommen...
2 CitationsSource
#1Janine Schniering (UZH: University of Zurich)H-Index: 3
#2Martina Benešová (ETH Zurich)H-Index: 7
Last. Britta Maurer (UZH: University of Zurich)H-Index: 22
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Background Interstitial lung disease (ILD) is a common and severe complication in rheumatic diseases. Folate receptor-β is expressed on activated, but not resting macrophages which play a key role in dysregulated tissue repair including ILD. We therefore aimed to pre-clinically evaluate the potential of 18F-AzaFol-based PET/CT (positron emission computed tomography/computed tomography) for the specific detection of macrophage-driven pathophysiologic processes in experimental ILD. Methods The pul...
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#1Magda Marcon (UZH: University of Zurich)H-Index: 8
#2Alexander Ciritsis (UZH: University of Zurich)H-Index: 5
Last. Andreas Boss (UZH: University of Zurich)H-Index: 33
view all 9 authors...
Our aims were to determine if features derived from texture analysis (TA) can distinguish normal, benign, and malignant tissue on automated breast ultrasound (ABUS); to evaluate whether machine learning (ML) applied to TA can categorise ABUS findings; and to compare ML to the analysis of single texture features for lesion classification. This ethically approved retrospective pilot study included 54 women with benign (n = 38) and malignant (n = 32) solid breast lesions who underwent ABUS. After m...
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#1Andreas Christe (University of Bern)H-Index: 24
#2Laura Naëmi Walti (University of Bern)H-Index: 1
Last. Lukas Ebner (University of Bern)H-Index: 10
view all 17 authors...
OBJECTIVES To investigate differences in chest computed tomography (CT) and chest radiographs (CXRs) of Pneumocystis jirovecii pneumonia (PJP) between renal transplant recipients (RTRs) and human immunodeficiency virus (HIV)-positive patients. METHODS From 2005 to 2012, 84 patients with PJP (RTR n = 24; HIV n = 60) were included in this retrospective multicentre study. Written informed consent was obtained. CT scans and CXRs were recorded within 2 weeks after the onset of symptoms. PJP diagnosis...
1 CitationsSource
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