Henner Hollert
RWTH Aachen University
Publications 463
#1Steve U. Ayobahan (Fraunhofer Society)H-Index: 1
#2Sebastian Eilebrecht (Fraunhofer Society)H-Index: 1
Last.Christoph Schäfers (Fraunhofer Society)H-Index: 15
view all 8 authors...
Abstract Measurement of specific biomarkers identified by proteomics provides a potential alternative method for risk assessment, which is required to discriminate between hepatotoxicity and endocrine disruption. In this study, adult zebrafish (Danio rerio) were exposed to the hepatotoxic substance acetaminophen (APAP) for 21 days, in a fish short-term reproduction assay (FSTRA). The molecular changes induced by APAP exposure were studied in liver and gonads by applying a previously developed co...
#1Leo Posthuma (Radboud University Nijmegen)H-Index: 35
#2Thomas Backhaus (University of Gothenburg)H-Index: 35
Last.Annemarie P. van Wezel (UvA: University of Amsterdam)H-Index: 26
view all 10 authors...
Present evaluations of chemical pollution in European surface and groundwater bodies focus on problem description and chemical classification of water quality. Surprisingly, relatively low attention has been paid to solutions of chemical pollution problems when those are encountered. Based on evaluations of current practices and available approaches, we suggest that water quality protection, monitoring, assessment and management of chemical pollution can be improved by implementing an early-stag...
8 CitationsSource
#1Matthias Liess (Helmholtz Centre for Environmental Research - UFZ)H-Index: 47
#2Toni RatteH-Index: 1
Last.Henner Hollert (RWTH Aachen University)H-Index: 50
view all 4 authors...
Pesticides contribute to this reduction of biodiversity in ecosystems. Obviously, environmental risk assessment did not prevent adverse pesticide effects on non-target organisms. This called for an identification of processes that are relevant to extrapolate from simplified investigations to the reality of pesticide effects in the field, one of the prominent research areas at the SETAC GLB since two decades. We identify research areas that are relevant to link toxicant effects from test systems ...
1 CitationsSource
#1Kirsten S. Jørgensen (SYKE: Finnish Environment Institute)H-Index: 26
#2Anne Kreutzer (Hamburg University of Applied Sciences)
Last.Feiyue Wang (UM: University of Manitoba)H-Index: 42
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This article introduces the EU Horizon 2020 research project GRACE (Integrated oil spill response actions and environmental effects), which focuses on a holistic approach towards investigating and understanding the hazardous impact of oil spills and the environmental impacts and benefits of a suite of marine oil spill response technologies in the cold climate and ice-infested areas of the North Atlantic and the Baltic Sea. The response methods considered include mechanical collection in water an...
#1Henner Hollert (RWTH Aachen University)H-Index: 50
#2Thomas Backhaus (University of Gothenburg)H-Index: 35
1 CitationsSource
#1Rolf Altenburger (Helmholtz Centre for Environmental Research - UFZ)H-Index: 47
#2Werner Brack (Helmholtz Centre for Environmental Research - UFZ)H-Index: 41
Last.Martin Krauss (Helmholtz Centre for Environmental Research - UFZ)H-Index: 36
view all 24 authors...
Environmental water quality monitoring aims to provide the data required for safeguarding the environment against adverse biological effects from multiple chemical contamination arising from anthropogenic diffuse emissions and point sources. Here, we integrate the experience of the international EU-funded project SOLUTIONS to shift the focus of water monitoring from a few legacy chemicals to complex chemical mixtures, and to identify relevant drivers of toxic effects. Monitoring serves a range o...
10 CitationsSource
#1Werner Brack (Helmholtz Centre for Environmental Research - UFZ)H-Index: 41
#2Selim Ait AissaH-Index: 1
Last.Rolf Altenburger (Helmholtz Centre for Environmental Research - UFZ)H-Index: 47
view all 19 authors...
The present monitoring and assessment of the chemical status of water bodies fail to characterize the likelihood that complex mixtures of chemicals affect water quality. The European Collaborative Project SOLUTIONS suggests that this likelihood can be estimated with effect-based methods (EBMs) complemented by chemical screening and/or impact modeling. These methods should be used to identify the causes of impacted water quality and to develop programs of measures to improve water quality. Along ...
18 CitationsSource
#1Jochen P. Zubrod (University of Koblenz and Landau)H-Index: 16
#2Rolf-Alexander Düring (University of Giessen)H-Index: 16
Last.Henner Hollert (RWTH Aachen University)H-Index: 50
view all 12 authors...
This editorial presents the objectives and achievements of the German Language Branch of the Society of Environmental Toxicology and Chemistry Europe (SETAC GLB), a regional branch of SETAC Europe, of the last 20 years. SETAC GLB serves Germany, Austria, and Switzerland, by providing an open forum for research related to ecotoxicology and environmental chemistry, to the sustainable management and regulation of natural resources, to education in environmental sciences, as well as to issues relate...
#1Steve U. Ayobahan (Fraunhofer Society)H-Index: 1
#2Elke Eilebrecht (Fraunhofer Society)H-Index: 1
Last.Christoph Schäfers (Fraunhofer Society)H-Index: 15
view all 9 authors...
The fish short-term reproduction assay (FSTRA) is a common in vivo screening assay for assessing endocrine effects of chemicals on reproduction in fish. However, the current reliance on measures such as egg number, plasma vitellogenin concentration and morphological changes to determine endocrine effects can lead to false labelling of chemicals with non-endocrine modes- of-action. Here, we integrated quantitative liver and gonad shotgun proteomics into the FSTRA in order to investigate the causa...
1 CitationsSource
#1Riccardo Massei (Helmholtz Centre for Environmental Research - UFZ)H-Index: 6
#2Henner Hollert (RWTH Aachen University)H-Index: 50
Last.Werner Brack (Helmholtz Centre for Environmental Research - UFZ)H-Index: 41
view all 10 authors...
The toxicological characterization of sediments is an essential task to monitor the quality of aquatic environments. Many hazardous pollutants may accumulate in sediments and pose a risk to the aqu ...
1 CitationsSource