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Esther E. Bron
Erasmus University Rotterdam
47Publications
12H-index
563Citations
Publications 47
Newest
Published on Mar 11, 2019in European Radiology3.96
Rozanna Meijboom5
Estimated H-index: 5
(EUR: Erasmus University Rotterdam),
Rebecca M. E. Steketee6
Estimated H-index: 6
(EUR: Erasmus University Rotterdam)
+ 5 AuthorsMarion Smits25
Estimated H-index: 25
(EUR: Erasmus University Rotterdam)
Objectives This study explored group-wise quantitative measures of tract-specific white matter (WM) microstructure and functional default mode network (DMN) connectivity to establish an initial indication of their clinical applicability for early-stage and follow-up differential diagnosis of Alzheimer’s disease (AD) and behavioural variant frontotemporal dementia (bvFTD).
Published on May 23, 2019in Journal of Neurology, Neurosurgery, and Psychiatry8.27
Lieke H.H. Meeter7
Estimated H-index: 7
(EUR: Erasmus University Rotterdam),
Rebecca M. E. Steketee6
Estimated H-index: 6
(EUR: Erasmus University Rotterdam)
+ 44 AuthorsNicholas Olney2
Estimated H-index: 2
(UCSF: University of California, San Francisco)
Background: Semantic dementia (SD) is a neurodegenerative disorder characterised by progressive language problems falling within the clinicopathological spectrum of frontotemporal lobar degeneration (FTLD). The development of disease-modifying agents may be facilitated by the relative clinical and pathological homogeneity of SD, but we need robust monitoring biomarkers to measure their efficacy. In different FTLD subtypes, neurofilament light chain (NfL) is a promising marker, therefore we inves...
Published on Aug 26, 2019in arXiv: Image and Video Processing
Bo B. Li , Marius de Groot11
Estimated H-index: 11
+ 3 AuthorsEsther E. Bron12
Estimated H-index: 12
(EUR: Erasmus University Rotterdam)
Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white matter tract in diffusion tensor MRI data. Methods based on the tractography are popular for white matter tract segmentation. However, because of the limited consistency and long processing time, such methods may not be suitable for clinical practice. We therefo...
Published on Jul 16, 2019in International Journal of Cardiovascular Imaging1.86
Wieneke Vlastra3
Estimated H-index: 3
(UvA: University of Amsterdam),
Thomas van den Boogert1
Estimated H-index: 1
(UvA: University of Amsterdam)
+ 13 AuthorsAart J. Nederveen34
Estimated H-index: 34
(UvA: University of Amsterdam)
Published on Jun 2, 2019
Vikram Venkatraghavan2
Estimated H-index: 2
(EUR: Erasmus University Rotterdam),
Florian Dubost4
Estimated H-index: 4
(EUR: Erasmus University Rotterdam)
+ 3 AuthorsStefan Klein25
Estimated H-index: 25
(EUR: Erasmus University Rotterdam)
Event-based models (EBM) are a class of disease progression models that can be used to estimate temporal ordering of neuropathological changes from cross-sectional data. Current EBMs only handle scalar biomarkers, such as regional volumes, as inputs. However, regional aggregates are a crude summary of the underlying high-resolution images, potentially limiting the accuracy of EBM. Therefore, we propose a novel method that exploits high-dimensional voxel-wise imaging biomarkers: n-dimensional dis...
Published on Jan 1, 2019in arXiv: Learning
Vikram Venkatraghavan2
Estimated H-index: 2
(EUR: Erasmus University Rotterdam),
Florian Dubost4
Estimated H-index: 4
+ 3 AuthorsStefan Klein25
Estimated H-index: 25
Event-based models (EBM) are a class of disease progression models that can be used to estimate temporal ordering of neuropathological changes from cross-sectional data. Current EBMs only handle scalar biomarkers, such as regional volumes, as inputs. However, regional aggregates are a crude summary of the underlying high-resolution images, potentially limiting the accuracy of EBM. Therefore, we propose a novel method that exploits high-dimensional voxel-wise imaging biomarkers: n-dimensional dis...
Published on Feb 1, 2019in NeuroImage5.81
Vikram Venkatraghavan2
Estimated H-index: 2
(EUR: Erasmus University Rotterdam),
Esther E. Bron12
Estimated H-index: 12
(EUR: Erasmus University Rotterdam)
+ 1 AuthorsStefan Klein25
Estimated H-index: 25
(EUR: Erasmus University Rotterdam)
Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in which biomarkers for a disease become abnormal based on cross-sectional data. It can help in understanding the dynamics of disease progression and facilitate early diagnosis and prognosis by staging patients. In this work we propose a novel discriminative approach...
Published on Jan 1, 2019in arXiv: Image and Video Processing
Bo B. Li (EUR: Erasmus University Rotterdam), Wiro J. Niessen4
Estimated H-index: 4
+ 4 AuthorsEsther E. Bron12
Estimated H-index: 12
To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components. Registration between time-points is used either as a prior for segmentation in a subsequent time point or to perform segmentation in a common space. In this work, we propose a novel hybrid convolutional neural network (CNN) that integrates segmentation and reg...
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