CancerEndocrinologyProspective cohort studyBreast cancerMedicine
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Publications 468
#1Deanna Blansky (Albert Einstein College of Medicine)
#2Ioannis Mantzaris (Albert Einstein College of Medicine)H-Index: 10
Last. H. Dean Hosgood (Albert Einstein College of Medicine)H-Index: 37
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Abstract Introduction Exposure to lymphomagens vary by geography. The extent to which these contribute to racial and ethnic disparities in non-Hodgkin lymphoma (NHL) incidence is not well understood. We sought to evaluate the association between urban-rural status and racial and ethnic disparities in the three major NHL subtypes - diffuse large B cell lymphoma (DLBCL), follicular lymphoma (FL), and chronic lymphocytic leukemia (CLL). Materials and Methods We used data on NHL incidence from 21 Su...
#1Sarah S. JacksonH-Index: 6
#2Hans-Olov Adami (KI: Karolinska Institutet)H-Index: 128
Last. Gretchen L. GierachH-Index: 20
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Abstract Background Gallbladder cancer (GBC) has a female predominance, although other biliary tract cancers (BTCs) such as extrahepatic and intrahepatic bile duct (EHBDC and IHBDC) and ampulla of Vater (AVC) have a male predominance. The role of female reproductive factors in BTC etiology remains unclear. Methods We pooled data from 19 studies of >1.5 million women participating in the Biliary Tract Cancers Pooling Project to examine the associations of parity, age at menarche, reproductive yea...
#1Jessica L. Petrick (BU: Boston University)H-Index: 14
#2Úna C. McMenaminH-Index: 5
Last. Lynn Rosenberg (BU: Boston University)H-Index: 82
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Intrahepatic cholangiocarcinoma (ICC) arises from cholangiocytes in the intrahepatic bile duct and is the second most common type of liver cancer. Cholangiocytes express both oestrogen receptor-α and -β, and oestrogens positively modulate cholangiocyte proliferation. Studies in women and men have reported higher circulating oestradiol is associated with increased ICC risk, further supporting a hormonal aetiology. However, no observational studies have examined the associations between exogenous ...
#1Madelyn Klugman (Albert Einstein College of Medicine)H-Index: 1
#2Xiaonan Xue (Albert Einstein College of Medicine)H-Index: 35
Last. H. Dean Hosgood (Albert Einstein College of Medicine)H-Index: 37
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Background Hispanics/Latinos are a growing yet understudied population in the United States (US). Despite lower socioeconomic status, Hispanics/Latinos tend to have similar or better health outcomes than Non-Hispanic Whites (NHWs). This phenomenon has not been conclusively studied for lung cancer.
#1David Entenberg (Albert Einstein College of Medicine)H-Index: 20
#2Maja H. OktayH-Index: 17
Last. John S. CondeelisH-Index: 91
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Metastasis causes ~90% of breast cancer mortality. However, standard prognostic tests based mostly on proliferation genes do not measure metastatic potential. Tumor MicroEnvironment of Metastasis (TMEM), an immunohistochemical biomarker for doorways on blood vessels that support tumor cell dissemination is prognostic for metastatic outcome in breast cancer patients. Studies quantifying TMEM doorways have involved manual scoring by pathologists utilizing static digital microscopy: a labor-intensi...
#1Rita Peila (Albert Einstein College of Medicine)H-Index: 1
#2TomRohan (Albert Einstein College of Medicine)H-Index: 74
Background: Evidence suggest that diabetes and glycated hemoglobin (HbA1c) levels are associated with cancer risk. However, previous studies have been limited variably by failure to adjust for cancer-specific risk factors (e.g., body mass index), inattention to diabetes duration and use of anti-diabetic medications, and failure to stratify by obesity. Methods: We examined the association between diabetes, HbA1c, and cancer risk in the UK Biobank, using data from 476,517 participants (54% women),...
#1Rhonda Arthur (Albert Einstein College of Medicine)H-Index: 5
#2Xiaonan Xue (Albert Einstein College of Medicine)H-Index: 35
Last. TomRohan (Albert Einstein College of Medicine)H-Index: 74
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Background:Sex steroid hormones and sex hormone-binding globulin (SHBG) have been implicated in the etiology of invasive breast cancer, but their associations with risk of the precursor lesion, ductal carcinoma in situ (DCIS) of the breast, remain unclear. Methods:We used Cox proportional hazards regression models to estimate the associations of serum levels of estradiol (premenopausal women only), testosterone and/or SHBG with DCIS risk among 182,935 women. After a median follow-up of 7.1 years...
#1Rowan T. ChlebowskiH-Index: 78
Last. Dorothy L. LaneH-Index: 1
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#1Rowan T. Chlebowski (Los Angeles Biomedical Research Institute)H-Index: 78
#2Aaron K. Aragaki (Fred Hutchinson Cancer Research Center)H-Index: 40
Last. Karen C. Johnson (UTHSC: University of Tennessee Health Science Center)H-Index: 71
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PURPOSEObservational studies of dietary fat intake and breast cancer have reported inconsistent findings. This topic was addressed in additional analyses of the Women’s Health Initiative (WHI) Diet...
#1Minouk J. Schoemaker (ICR: Institute of Cancer Research)H-Index: 44
#2Hazel B. Nichols (UNC: University of North Carolina at Chapel Hill)H-Index: 16
Last. Kimberly A. Bertrand (BU: Boston University)H-Index: 23
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Early-adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual-level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk factors and breast cancer subtype. Hazard ratios (HR) and 95% confidence intervals (CI) were obtaine...