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Chiara Gamberi
Concordia University
19Publications
9H-index
658Citations
Publications 19
Newest
Published on Apr 30, 2019in Journal of Mass Spectrometry 2.11
Ethan Yang1
Estimated H-index: 1
(Université de Montréal),
Chiara Gamberi9
Estimated H-index: 9
(Concordia University),
Pierre Chaurand15
Estimated H-index: 15
(Université de Montréal)
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Published on Jan 2, 2019in International Journal of Science Education 1.32
Chiara Gamberi9
Estimated H-index: 9
(Concordia University),
Katharine Hall1
Estimated H-index: 1
(Concordia University)
The design and implementation of a scientific writing assignment in a >100 student upper-level undergraduate microbiology class resulted in a peer-reviewed publication in an open-access journal. The primary course objectives and requirements were met by assigning groups of four to five students one of 25 distinct section topics of similar size and complexity that complemented the course materials. Students were taught to identify, read and cite primary scientific literature, to avoid plagiarism,...
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Published on May 31, 2018in BioMed Research International 2.58
Cassandra Millet-Boureima1
Estimated H-index: 1
(Concordia University),
Jessica Porras Marroquin1
Estimated H-index: 1
(Concordia University),
Chiara Gamberi9
Estimated H-index: 9
(Concordia University)
Detoxification is a fundamental function for all living organisms that need to excrete catabolites and toxins to maintain homeostasis. Kidneys are major organs of detoxification that maintain water and electrolyte balance to preserve physiological functions of vertebrates. In insects, the renal function is carried out by Malpighian tubules and nephrocytes. Due to differences in their circulation, the renal systems of mammalians and insects differ in their functional modalities, yet carry out sim...
2 Citations Source Cite
Published on Jul 17, 2017in Frontiers in Microbiology 4.02
Susannah Selber-Hnatiw1
Estimated H-index: 1
(Concordia University),
Belise Rukundo1
Estimated H-index: 1
(Concordia University)
+ 100 AuthorsAlexandra Baird1
Estimated H-index: 1
(Concordia University)
Composed of trillions of individual microbes, the human gut microbiota has adapted to the uniquely diverse environments found in the human intestine. Quickly responding to the variances in the ingested food, the microbiota interacts with the host via reciprocal biochemical signaling to coordinate the exchange of nutrients and proper immune function. Host and microbiota function as a unit which guards its balance against invasion by potential pathogens and which undergoes natural selection. Distu...
17 Citations Source Cite
Published on Apr 13, 2017in PLOS Genetics 5.54
Chiara Gamberi9
Estimated H-index: 9
,
David R. Hipfner5
Estimated H-index: 5
+ 1 AuthorsWilliam D. Lubell1
Estimated H-index: 1
Progressive cystic kidney degeneration underlies diverse renal diseases, including the most common cause of kidney failure, autosomal dominant Polycystic Kidney Disease (PKD). Genetic analyses of patients and animal models have identified several key drivers of this disease. The precise molecular and cellular changes underlying cystogenesis remain, however, elusive. Drosophila mutants lacking the translational regulator Bicaudal C (BicC, the fly ortholog of vertebrate BICC1 implicated in renal c...
6 Citations Source Cite
Published on Feb 1, 2016in Developmental Biology 3.26
Luca Valzania5
Estimated H-index: 5
(University of Bologna),
Hajime Ono12
Estimated H-index: 12
(Kyoto University)
+ 5 AuthorsGiuseppe Gargiulo21
Estimated H-index: 21
(University of Bologna)
Abstract Maternal expression of the translational regulator 4EHP (eIF4E-Homologous Protein) has an established role in generating protein gradients essential for specifying the Drosophila embryonic pattern. We generated a null mutation of 4EHP , which revealed for the first time that it is essential for viability and for completion of development. In fact, 4EHP null larvae, and larvae ubiquitously expressing RNAi targeting 4EHP , are developmentally delayed, fail to grow and eventually die. In a...
8 Citations Source Cite
Published on Dec 1, 2015
Analysis of Drosophila cuticular structures is a classic genetic tool to infer the efficiency of developmental processes via careful morphological evaluation. When performing genetic screens in pursuit of mutations with developmental effects or during mutational scanning to identify functionally important protein domains, high throughput analyses of cuticles from numerous fly lines becomes necessary. To increase throughput ingenious structures of fly containers have been devised such as fly “con...
Published on Dec 19, 2013in PLOS Genetics 5.54
Jordi Solana11
Estimated H-index: 11
(University of Nottingham),
Chiara Gamberi9
Estimated H-index: 9
(McGill University)
+ 5 AuthorsA. Aziz Aboobaker23
Estimated H-index: 23
(University of Oxford)
Post-transcriptional regulatory mechanisms are of fundamental importance to form robust genetic networks, but their roles in stem cell pluripotency remain poorly understood. Here, we use freshwater planarians as a model system to investigate this and uncover a role for CCR4-NOT mediated deadenylation of mRNAs in stem cell differentiation. Planarian adult stem cells, the so-called neoblasts, drive the almost unlimited regenerative capabilities of planarians and allow their ongoing homeostatic tis...
15 Citations Source Cite
Published on Jan 1, 2012in Comparative and Functional Genomics 1.90
Chiara Gamberi9
Estimated H-index: 9
,
Paul Lasko49
Estimated H-index: 49
Regulation of mRNA translation is especially important during cellular and developmental processes. Many evolutionarily conserved proteins act in the context of multiprotein complexes and modulate protein translation both at the spatial and the temporal levels. Among these, Bicaudal C constitutes a family of RNA binding proteins whose founding member was first identified in Drosophila and contains orthologs in vertebrates. We discuss recent advances towards understanding the functions of these p...
12 Citations Source Cite
Published on Jul 1, 2009in Development Genes and Evolution 2.13
Maria Gabriella Maurizii6
Estimated H-index: 6
(University of Bologna),
Valeria Cavaliere9
Estimated H-index: 9
(University of Bologna)
+ 3 AuthorsCarlo Taddei10
Estimated H-index: 10
(University of Bologna)
The vasa gene, first identified in Drosophila, is a key determinant for germline formation in eukaryotes. Homologs of vasa have been identified and linked to germline development, in many invertebrates and vertebrates. Here, we analyze the distribution of Vasa in early germ cells (oogonia and oocytes) and previtellogenic ovarian follicles of the lizard Podarcis sicula. During most of its previtellogenic growth, the oocyte in this lizard species is structurally and functionally integrated through...
9 Citations Source Cite
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