Thomas D. Marcotte
University of California, San Diego
Publications 136
Published on Sep 3, 2019in AIDS Research and Human Retroviruses1.80
Aura Temereanca5
Estimated H-index: 5
(UMFCD: Carol Davila University of Medicine and Pharmacy),
Luminita Ene8
Estimated H-index: 8
+ 8 AuthorsCristian L. Achim37
Estimated H-index: 37
(UCSD: University of California, San Diego)
HIV-associated neurocognitive disorders (HAND) continue to be reported even in patients with successful antiretroviral treatment. We investigated the prevalence of neurocognitive impairment and pos...
Published on Apr 1, 2019in Journal of Acquired Immune Deficiency Syndromes3.86
Raha Dastgheyb2
Estimated H-index: 2
Ned Sacktor51
Estimated H-index: 51
+ 7 AuthorsNorman J. Haughey30
Estimated H-index: 30
Published on 2019in Journal of NeuroVirology2.30
Ruxandra Burlacu2
Estimated H-index: 2
Anya Umlauf15
Estimated H-index: 15
+ 7 AuthorsLuminita Ene8
Estimated H-index: 8
Published on Jun 1, 2019in The Lancet HIV14.75
Alessandro Livelli , Florin Vaida37
Estimated H-index: 37
(UCSD: University of California, San Diego)
+ 34 AuthorsJustin C. McArthur96
Estimated H-index: 96
(Johns Hopkins University)
Summary Background Few large projects have evaluated the factors that influence the HIV RNA concentrations (viral load) in cerebrospinal fluid (CSF) during antiretroviral therapy (ART) over time. We aimed to determine the correlates of HIV RNA in CSF in a large cohort. Methods We analysed longitudinal data from adults living with HIV in the US CHARTER cohort. Participants in the CHARTER study were recruited from six US academic medical centres—in Baltimore (MD), Galveston (TX), New York (NY), St...
Published on Apr 1, 2019in Clinica Chimica Acta2.73
Philip M. Sobolesky1
Estimated H-index: 1
(UCSD: University of California, San Diego),
Breland E. Smith1
Estimated H-index: 1
(UCSD: University of California, San Diego)
+ 5 AuthorsRobert L. Fitzgerald28
Estimated H-index: 28
(UCSD: University of California, San Diego)
Abstract A liquid chromatography tandem mass spectrometry method was developed for quantifying ten cannabinoids in oral fluid (OF). This method utilizes OF collected by the Quantisal™ device and concurrently quantifies cannabinol (CBN), cannabidiol (CBD), Δ 9 -tetrahydrocannabinol (THC), 11-hydroxy-Δ 9 -THC (11-OH-THC), 11-nor-9-carboxy-Δ 9 -THC (THC-COOH), 11-nor-9-carboxy-Δ 9 -THC glucuronide (THC-COOH-gluc), Δ 9 -THC glucuronide (THC-gluc), cannabigerol (CBG), tetrahydrocannabiverin (THCV), a...
Published on Mar 19, 2019in Neurology8.69
Saja S. Khuder , Suming Chen + 14 AuthorsLisa Jacobson68
Estimated H-index: 68
Objective To determine the association of insulin sensitivity and metabolic status with declining cognition in HIV-infected individuals. Methods We conducted targeted clinical and metabolic measures in longitudinal plasma samples obtained from HIV-infected patients enrolled in the Central Nervous System HIV Anti-Retroviral Therapy Effects Research Study (CHARTER). Findings were validated with plasma samples from the Multicenter AIDS Cohort Study (MACS). Patients were grouped according to longitu...
Published on Mar 1, 2019
Griffin A. Tyree (UCSD: University of California, San Diego), A TyreeGriffin (UCSD: University of California, San Diego)+ 8 AuthorsAtkinsonJoseph Hampton (UCSD: University of California, San Diego)
Abstract Background: A recent meta-analysis affirmed the benefit of medicinal cannabis for chronic neuropathic pain, a disabling and difficult-to-treat condition. As medicinal cannabis use is becom...
Published on Feb 1, 2019in Journal of NeuroVirology2.30
Aljoharah Alakkas1
Estimated H-index: 1
(UCSD: University of California, San Diego),
Ronald J. Ellis62
Estimated H-index: 62
(UCSD: University of California, San Diego)
+ 16 AuthorsBenjamin B. Gelman38
Estimated H-index: 38
(UTMB: University of Texas Medical Branch)
HIV-associated neurocognitive disorders (HANDs) persist even with virologic suppression on combination antiretroviral therapy (cART), and the underlying pathophysiological mechanisms are not well understood. We performed structural magnetic resonance imaging and MR spectroscopy (MRS) in HIV+ individuals without major neurocognitive comorbidities. Study participants were classified as neurocognitively unimpaired (NU), asymptomatic (ANI), mild neurocognitive disorder (MND), or HIV­associated demen...
Published on Feb 1, 2019in Journal of Acquired Immune Deficiency Syndromes3.86
Jibreel Jumare6
Estimated H-index: 6
Samer S. El-Kamary21
Estimated H-index: 21
+ 15 AuthorsScott Letendre48
Estimated H-index: 48
Author(s): Jumare, Jibreel; El-Kamary, Samer S; Magder, Laurence; Hungerford, Laura; Umlauf, Anya; Franklin, Donald; Ghate, Manisha; Abimiku, Alash'le; Charurat, Man; Letendre, Scott; Ellis, Ronald J; Mehendale, Sanjay; Blattner, William A; Royal, Walter; Marcotte, Thomas D; Heaton, Robert K; Grant, Igor; McCutchan, J Allen | Abstract: BACKGROUND:Risk of cognitive impairment is increased among persons with high or low body mass index (BMI) in HIV- and HIV+ populations in resource-rich settings. ...
Published on Jan 15, 2019in Frontiers in Human Neuroscience2.87
Greg Rupp , Chris Berka15
Estimated H-index: 15
+ 7 AuthorsThomas D. Marcotte44
Estimated H-index: 44
(UCSD: University of California, San Diego)
The number of older drivers is steadily increasing, and advancing age is associated with a high rate of automobile crashes and fatalities. This can be attributed to a combination of factors including decline in sensory, motor, and cognitive functions due to natural ageing or neurodegenerative diseases such as HIV-Associated Neurocognitive Disorder (HAND). Current clinical assessment methods only modestly predict impaired driving. Thus, there is a need for inexpensive and scalable tools to predic...