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Roman Romero-Ortuno
Mercer University
Physical therapyPopulationDiabetes mellitusMedicineGerontology
104Publications
21H-index
1,416Citations
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Publications 114
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#1Teodoro J. Oscanoa (UNMSM: National University of San Marcos)H-Index: 5
#2Edwin Cieza (UNMSM: National University of San Marcos)
Last. Roman Romero-Ortuno (Mercer University)H-Index: 21
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Background: Some studies have suggested that the insertion(I)/deletion(D) polymorphism of the Angiotensin-Converting Enzyme (ACE) gene may be associated with human longevity, especially in centenarians. However, this association is still controversial. Besides, there have been no studies in Peruvians.Aim: To describe the age distribution of the ACE polymorphism in a convenience sample of Peruvian older people.Subjects and methods: This was a cross-sectional study in 104 Geriatric Day Hospital pa...
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#1Aisling O'HalloranH-Index: 12
Last. Roseanne M. KennyH-Index: 1
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#1Stephen H.-F. Macdonald (UCD: University College Dublin)H-Index: 1
#2John Travers (UCD: University College Dublin)H-Index: 1
Last. Marie Therese CooneyH-Index: 2
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Introduction The best interventions to address frailty among older adults have not yet been fully defined, and the diversity of interventions and outcome measures makes this process challenging. Consequently, there is a lack of guidance for clinicians and researchers regarding which interventions are most likely to help older persons remain robust and independent. This paper uses meta-analysis to assess effectiveness of primary care interventions for physical frailty among community-dwelling adu...
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#1Peter Hartley (University of Cambridge)H-Index: 3
#2Roman Romero-Ortuno (Trinity College, Dublin)H-Index: 21
Last. Christi Deaton (University of Cambridge)H-Index: 12
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#1Giulia Rivasi (UniFI: University of Florence)H-Index: 1
#2Rose Anne Kenny (Mercer University)H-Index: 66
Last. Roman Romero-Ortuno (Mercer University)H-Index: 21
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Abstract Background Older people taking benzodiazepines (BDZs) have higher risk of falling, which is mainly attributed to cognitive and psychomotor effects. BDZs may also have hypotensive effects. We investigated the association between BDZs and orthostatic blood pressure behaviour in older people. Methods We retrospectively analysed data from an outpatient clinic where people aged 60 or older underwent a geriatric assessment. Non-invasive beat-to-beat orthostatic systolic blood pressure (SBP) w...
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#1Teodoro J. Oscanoa (Universidad de San Martín de Porres)H-Index: 5
#2José P. Amado (Universidad de San Martín de Porres)H-Index: 1
Last. Roman Romero-Ortuno (Trinity College, Dublin)H-Index: 21
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BACKGROUND: Antihypertensive medications may reduce the incidence of cognitive disorders. This may be due to reasons beyond their pure hypotensive effect. This study aimed to systematically review the association between the use of Angiotensin-Receptor Blockers (ARBs)and the incidence of Alzheimer's Disease (AD). METHODS: We systematically searched studies reporting the association between ARB use and incidence of AD. RESULTS: Ten studies (1 RCT, 2 case-control studies and 7 cohort studies) met ...
1 CitationsSource
#1Nicholas R. Evans (University of Cambridge)H-Index: 8
Last. Elizabeth A. Warburton (University of Cambridge)H-Index: 44
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BACKGROUND: Clinical frailty is an important syndrome for clinical care and research, independently predicting mortality and rates of institutionalisation in a range of medical conditions. However, there has been little research into the role of frailty in stroke. OBJECTIVE: This study investigates the effect of frailty on 28-day mortality following ischaemic stroke and outcomes following stroke thrombolysis. METHODS: Frailty was measured using the Clinical Frailty Scale (CFS) for all ischaemic ...
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#1Roman Romero-Ortuno (Trinity College, Dublin)H-Index: 21
#2Rose Anne Kenny (Trinity College, Dublin)H-Index: 66
Last. Ross McManus (Trinity College, Dublin)H-Index: 38
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Abstract Collagens and elastin are ‘building blocks’ of tissues and extracellular matrix. Mutations in these proteins cause severe congenital syndromes. Adverse genetic variations may accelerate the aging process in adults contributing to premature morbidity, disability and/or mortality. Favorable variants may contribute to longevity and/or healthy aging, but this is much less studied. We reviewed the association between variation in the genes of collagens and elastin and premature aging, accele...
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#1Roman Romero-Ortuno (Trinity College, Dublin)H-Index: 21
#2Siobhan Scarlett (Trinity College, Dublin)H-Index: 1
Last. Rose Anne Kenny (Trinity College, Dublin)H-Index: 66
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BACKGROUND: Fried's frailty phenotype is defined by five criteria: exhaustion, unexplained weight loss, weakness, slowness and low physical activity. Prefrailty (PF) meets one or two criteria. PF is of interest as a target for preventative interventions, but it is not known if it is a homogenous syndrome. OBJECTIVE: to compare the longitudinal trajectories of two PF groups: one defined by exhaustion and/or unexplained weight loss (PF1) and one defined by one or two of the following: weakness, sl...
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#1Eoin Duggan (Mercer University)H-Index: 3
#1Eoin Duggan (Mercer University)
Last. Rose Anne Kenny (Mercer University)H-Index: 66
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Objectives To determine whether admissions for orthostatic hypotension (OH) and its consequences, such as falls, have changed over the past 10 years in the National Health Service (NHS) England. Setting Data from NHS England Hospital Episode Statistics, a database containing details of all admissions, accident and emergency attendances and outpatient appointments at NHS hospitals in England, were obtained and analysed. Participants Data on hospital admissions in NHS England, as defined by finish...
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